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NCT07217990 · ClinicalTrials.gov registry record · Phase 1

Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer

A Phase 1 study, sponsored by Ohio State University Comprehensive Cancer Center.

Not yet
Registry status
Phase 1
Development phase
84
Enrollment target

NCT07217990: Clinical Trial Phase 1 study, sponsored by Ohio State University Comprehensive Cancer Center.

NCT07217990 is a Phase 1 study that has not yet begun recruiting, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 84 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07217990, a Phase 1 study, has not yet begun recruiting, sponsored by Ohio State University Comprehensive Cancer Center.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
84 participants
Enrollment target

Study Summary

This study will evaluate the efficacy and non-inferiority of a non-surgical approach for the treatment of patients with locally advanced breast cancer.

Primary Outcome

The study endpoints of disease-free rate and locoregional control will be determined in patient follow up by utilizing MRIs, annual mammograms and clinical assessments in conjunction with ctDNA status.

Interventions

  • PROCEDURE Biopsy
  • RADIATION Radiation Therapy
  • PROCEDURE MRI
  • DRUG Neoadjuvant Chemotherapy
  • PROCEDURE Breast Cancer Surgery

Trial Details

FieldValue
Enrollment Target 84 participants
Start Date 2026-09-15
Est. Completion 2027-12-31
Phase Phase 1

What is known before NCT07217990 opens enrollment

NCT07217990 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 84 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% higher).

The record links to 0 conditions, and to 5 interventions - of which Biopsy is the first listed.

NCT07217990 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07217990 about?

NCT07217990 is a clinical study titled "Neoadjuvant Complete Response Customized Treatment Approach for Definitive Management of Breast Cancer". This study will evaluate the efficacy and non-inferiority of a non-surgical approach for the treatment of patients with locally advanced breast cancer.

What is the current status of trial NCT07217990?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 84 participants. The study started on 2026-09-15. Estimated completion is 2027-12-31.

What interventions are being tested in trial NCT07217990?

The interventions under investigation include: Biopsy (PROCEDURE), Radiation Therapy (RADIATION), MRI (PROCEDURE), Neoadjuvant Chemotherapy (DRUG), Breast Cancer Surgery (PROCEDURE).

Who is sponsoring clinical trial NCT07217990?

This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07217990's enrollment target sits among peer trials

84 659th of 2000 higher than 1,336 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07217990, the US trial registry maintained by the National Library of Medicine. NCT07217990 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.