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NCT07217223 · ClinicalTrials.gov registry record · NA

Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study

A NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD), sponsored by University of California, San Diego.

Recruiting
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT07217223 is a NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD) that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 10 participants, below the 158-participant average among 22 other Major Depressive Disorder (MDD) trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07217223, a NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD), is actively recruiting participants, sponsored by University of California, San Diego.

RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

The investigators propose a single-arm, open-label study to evaluate the effectiveness, safety, tolerability and feasibility of at-home transcranial direct current stimulation (tDCS) as a treatment for depression, particularly in cases where patients have not responded well to traditional therapies. Treatment will be delivered over a 2-week period with daily weekday treatments i.e., five tDCS sessions, each lasting 20 minutes, spaced by approximately 20-minute inter-session intervals, for a total of three hours a day. Participants will self-administer treatment at home under direct remote supervision. Pre- and post- treatment neurophysiological biomarkers sessions will also be carried out. The study aims to examine changes in mood, brain activity, and related clinical outcomes before, during, and after treatment, with the goal to provide more information that can be used for future studies. PLEASE NOTE: THERE WILL BE 4 APPOINTMENTS THAT MUST OCCUR IN PERSON IN SAN DIEGO, CA.

Conditions Studied

Major Depressive Disorder (MDD) Treatment Resistant Depression (TRD)

Interventions

  • DEVICE Spaced Transcranial Direct Current Stimulation (tDCS)

Study Locations (1)

California

  • UCSD Interventional Psychiatry - San Diego

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2025-09-27
Est. Completion 2027-03
Phase NA

Sponsor

University of California, San Diego

775 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07217223

The ClinicalTrials.gov registry entry for NCT07217223 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 158-participant average among 22 other Major Depressive Disorder (MDD) trials with a reported enrollment target (94% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Major Depressive Disorder (MDD) appearing as the primary indexed condition, and to 1 intervention - of which Spaced Transcranial Direct Current Stimulation (tDCS) is the first listed.

NCT07217223 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT07217223 about?

NCT07217223 is a clinical study titled "Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study". The investigators propose a single-arm, open-label study to evaluate the effectiveness, safety, tolerability and feasibility of at-home transcranial direct current stimulation (tDCS) as a treatment for depression, particularly in cases where patients have not responded well to traditional therapies....

What is the current status of trial NCT07217223?

This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-09-27. Estimated completion is 2027-03.

What conditions does trial NCT07217223 study?

This clinical trial studies the following conditions: Major Depressive Disorder (MDD), Treatment Resistant Depression (TRD).

What interventions are being tested in trial NCT07217223?

The interventions under investigation include: Spaced Transcranial Direct Current Stimulation (tDCS) (DEVICE).

Who is sponsoring clinical trial NCT07217223?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07217223 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.