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NCT07217223 · ClinicalTrials.gov registry record · NA
Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study
A NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD), sponsored by University of California, San Diego.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT07217223: Recruiting NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD), sponsored by University of California, San Diego.
NCT07217223 is a NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD) that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 10 participants, below the 158-participant average among 22 other Major Depressive Disorder (MDD) trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07217223, a NA study of Major Depressive Disorder (MDD) and Treatment Resistant Depression (TRD), is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators propose a single-arm, open-label study to evaluate the effectiveness, safety, tolerability and feasibility of at-home transcranial direct current stimulation (tDCS) as a treatment for depression, particularly in cases where patients have not responded well to traditional therapies. Treatment will be delivered over a 2-week period with daily weekday treatments i.e., five tDCS sessions, each lasting 20 minutes, spaced by approximately 20-minute inter-session intervals, for a total of three hours a day. Participants will self-administer treatment at home under direct remote supervision. Pre- and post- treatment neurophysiological biomarkers sessions will also be carried out. The study aims to examine changes in mood, brain activity, and related clinical outcomes before, during, and after treatment, with the goal to provide more information that can be used for future studies. PLEASE NOTE: THERE WILL BE 4 APPOINTMENTS THAT MUST OCCUR IN PERSON IN SAN DIEGO, CA.
Primary Outcome
Recruitment rate will be measured as the number of patients enrolled by the conclusion of the study, reported as a whole number.
Conditions Studied
Interventions
- DEVICE Spaced Transcranial Direct Current Stimulation (tDCS)
Study Locations (1)
California
- UCSD Interventional Psychiatry - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-09-27 |
| Est. Completion | 2027-03 |
| Phase | NA |
What NCT07217223 shows while recruiting
NCT07217223 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 158-participant average among 22 other Major Depressive Disorder (MDD) trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Major Depressive Disorder (MDD) appearing as the primary indexed condition, and to 1 intervention - of which Spaced Transcranial Direct Current Stimulation (tDCS) is the first listed.
NCT07217223 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07217223 about?
NCT07217223 is a clinical study titled "Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety Study". The investigators propose a single-arm, open-label study to evaluate the effectiveness, safety, tolerability and feasibility of at-home transcranial direct current stimulation (tDCS) as a treatment for depression, particularly in cases where patients have not responded well to traditional therapies....
What is the current status of trial NCT07217223?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-09-27. Estimated completion is 2027-03.
What conditions does trial NCT07217223 study?
This clinical trial studies the following conditions: Major Depressive Disorder (MDD), Treatment Resistant Depression (TRD).
What interventions are being tested in trial NCT07217223?
The interventions under investigation include: Spaced Transcranial Direct Current Stimulation (tDCS) (DEVICE).
Who is sponsoring clinical trial NCT07217223?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07217223 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Major Depressive Disorder (MDD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07217223's enrollment target sits among peer trials
10 23rd of 22 the lowest of 22 other Major Depressive Disorder (MDD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Major Depressive Disorder (MDD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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