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NCT07211178 · ClinicalTrials.gov registry record
Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
A clinical trial of Breast Cancer and TNBC - Triple-Negative Breast Cancer, sponsored by Tempus AI.
- Recruiting
- Registry status
- 900
- Enrollment target
- 12
- Study locations
NCT07211178: Recruiting study of Breast Cancer and TNBC - Triple-Negative Breast Cancer, sponsored by Tempus AI.
NCT07211178 is a study of Breast Cancer and TNBC - Triple-Negative Breast Cancer that is actively recruiting participants, run by Tempus AI. The registered enrollment target is 900 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (68% lower). The trial reports 12 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07211178, a study of Breast Cancer and TNBC - Triple-Negative Breast Cancer, is actively recruiting participants, sponsored by Tempus AI.
- RECRUITING
- Registry status
- 900 participants
- Enrollment target
- 12
- Study locations
Study Summary
For patients with breast cancer, it's important to find any remaining cancer cells after they've had their main treatment. Even a few cells, called minimal residual disease (MRD), can lead to the cancer coming back later. A way to find these cells is by looking for tiny bits of cancer DNA that are shed into the blood. This is called circulating tumor DNA (ctDNA). A simple blood test, often called a liquid biopsy, can detect this ctDNA. This research aims to see if finding this cancer DNA in the blood can help predict if a patient's cancer will return. It also may help find out if the treatment is working. Ultimately, the results of this research may help doctors better manage breast cancer and develop new and improved tests and treatments.
Conditions Studied
Interventions
- OTHER There are no interventions in this observational study.
Study Locations (12)
Illinois
- Southern Illinois Hospital Services - Carbondale
- Cancer Care Specialist of Illinois - O'Fallon
Alabama
- Birmingham Hematology Associates - Birmingham
California
- PIH Health Whittier Hospital - Whittier
Indiana
- Goshen Center for Cancer Care - Goshen
Michigan
- Trinity Health - Ann Arbor
Missouri
- Oncology Hematology Associates - Springfield
Nevada
- Cancer Care Specialist of Reno - Reno
New Jersey
- Summit Medical Group - Florham Park
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 900 participants |
| Start Date | 2025-10-27 |
| Est. Completion | 2033-12 |
What NCT07211178 shows while recruiting
NCT07211178 is an observational study that tracks outcomes without assigning an intervention. The registered 900 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (68% lower).
The record links to 5 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which There are no interventions in this observational study. is the first listed.
NCT07211178 lists 12 locations in 11 states (Illinois, Alabama, California).
Frequently Asked Questions
What is clinical trial NCT07211178 about?
NCT07211178 is a clinical study titled "Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies". For patients with breast cancer, it's important to find any remaining cancer cells after they've had their main treatment. Even a few cells, called minimal residual disease (MRD), can lead to the cancer coming back later. A way to find these cells is by looking for tiny bits of cancer DNA that are ...
What is the current status of trial NCT07211178?
This trial is currently recruiting. The enrollment target is 900 participants. The study started on 2025-10-27. Estimated completion is 2033-12.
What conditions does trial NCT07211178 study?
This clinical trial studies the following conditions: Breast Cancer, TNBC - Triple-Negative Breast Cancer, Early Stage Breast Cancer, HER2 + Breast Cancer, HR Positive/HER-2 Negative Breast Cancer.
What interventions are being tested in trial NCT07211178?
The interventions under investigation include: There are no interventions in this observational study. (OTHER).
Who is sponsoring clinical trial NCT07211178?
This trial is sponsored by Tempus AI, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07211178 being conducted?
This trial has 12 study locations across Alabama, California, Illinois, Indiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07211178's enrollment target sits among peer trials
900 137th of 1224 higher than 1,087 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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