Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING

Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

NCT07211178 · View on ClinicalTrials.gov ↗

Study Summary

For patients with breast cancer, it's important to find any remaining cancer cells after they've had their main treatment. Even a few cells, called minimal residual disease (MRD), can lead to the cancer coming back later. A way to find these cells is by looking for tiny bits of cancer DNA that are shed into the blood. This is called circulating tumor DNA (ctDNA). A simple blood test, often called a liquid biopsy, can detect this ctDNA. This research aims to see if finding this cancer DNA in the blood can help predict if a patient's cancer will return. It also may help find out if the treatment is working. Ultimately, the results of this research may help doctors better manage breast cancer and develop new and improved tests and treatments.

Interventions

  • OTHER There are no interventions in this observational study.

Study Locations (12)

Illinois

  • Southern Illinois Hospital Services — Carbondale
  • Cancer Care Specialist of Illinois — O'Fallon

Alabama

  • Birmingham Hematology Associates — Birmingham

California

  • PIH Health Whittier Hospital — Whittier

Indiana

  • Goshen Center for Cancer Care — Goshen

Michigan

  • Trinity Health — Ann Arbor

Missouri

  • Oncology Hematology Associates — Springfield

Nevada

  • Cancer Care Specialist of Reno — Reno

New Jersey

  • Summit Medical Group — Florham Park

Trial Details

FieldValue
Enrollment Target 900 participants
Start Date 2025-10-27
Est. Completion 2033-12

Sponsor

Tempus AI

12 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07211178

The ClinicalTrials.gov registry entry for NCT07211178 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 900 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Tempus AI, which has 12 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention — of which There are no interventions in this observational study. is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07211178 reports 12 study locations spanning 11 distinct geographic areas — top geographies include Illinois, Alabama, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07211178 about?

NCT07211178 is a clinical study titled "Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies". For patients with breast cancer, it's important to find any remaining cancer cells after they've had their main treatment. Even a few cells, called minimal residual disease (MRD), can lead to the cancer coming back later. A way to find these cells is by looking for tiny bits of cancer DNA that are ...

What is the current status of trial NCT07211178?

This trial is currently recruiting. The enrollment target is 900 participants. The study started on 2025-10-27. Estimated completion is 2033-12.

What conditions does trial NCT07211178 study?

This clinical trial studies the following conditions: Breast Cancer, TNBC - Triple-Negative Breast Cancer, Early Stage Breast Cancer, HER2 + Breast Cancer, HR Positive/HER-2 Negative Breast Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07211178?

The interventions under investigation include: There are no interventions in this observational study. (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07211178?

This trial is sponsored by Tempus AI, which has 12 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07211178 being conducted?

This trial has 12 study locations across Alabama, California, Illinois, Indiana, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial