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RECRUITING Phase 2

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

NCT07196722 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in participants with moderately to severely active Crohn's disease (CD; a long-term condition causing severe inflammation of the intestinal tract).

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Icotrokinra

Study Locations (20)

California

  • Clinnova Research — Anaheim
  • Alliance Research Institute, LLC - Canoga Park — Canoga Park
  • Southern California Research Center — Coronado
  • Om Research, LLC 1 — Lancaster
  • TLC Clinical Research Inc — Los Angeles
  • GastroIntestinal Bioscience — Los Angeles
  • Om Research, LLC 2 — Oxnard
  • Clinical Applications Laboratories, Inc — San Diego
  • Medical Associates Research Group, Inc. — San Diego

Florida

  • American Institute of Research — Cutler Bay
  • Nature Coast Clinical Research — Inverness
  • Green Leaf Clinical Trials — Jacksonville
  • Florida Research Center Inc. — Lakewood Rch
  • Sanchez Clinical Research, Inc — Miami
  • GCP Clinical Research — Tampa

Arizona

  • AZ Gastro Care — Chandler
  • Mayo Clinic — Scottsdale

Colorado

  • Peak Gastroenterology Associates — Colorado Springs

Connecticut

  • Nuvance Health Danbury Hospital — Danbury

Georgia

  • Children's Center for Digestive Health Care — Atlanta

Trial Details

FieldValue
Enrollment Target 1,092 participants
Start Date 2025-10-03
Est. Completion 2032-10-06
Phase Phase 2

Sponsor

Janssen Research & Development

442 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07196722

The ClinicalTrials.gov registry entry for NCT07196722 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,092 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Crohn Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07196722 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07196722 about?

NCT07196722 is a clinical study titled "A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease". The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in participants with moderately to severely active Crohn's disease (CD; a long-term condition causing severe inflammation of the intestinal tract).

What is the current status of trial NCT07196722?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 1,092 participants. The study started on 2025-10-03. Estimated completion is 2032-10-06.

What conditions does trial NCT07196722 study?

This clinical trial studies the following conditions: Crohn Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07196722?

The interventions under investigation include: Placebo (DRUG), Icotrokinra (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07196722?

This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07196722 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial