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NCT04590508 · ClinicalTrials.gov registry record · Phase 2

A Phase 2 Clinical Trial: Xanthohumol Metabolism and Signature (XMaS) in Crohn's Disease

A Phase 2 study of Crohn Disease, sponsored by National University of Natural Medicine.

Active
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT04590508 is a Phase 2 study of Crohn Disease that is active but no longer recruiting, run by National University of Natural Medicine. The registered enrollment target is 20 participants, below the 205-participant average among 71 other Crohn Disease trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04590508, a Phase 2 study of Crohn Disease, is active but no longer recruiting, sponsored by National University of Natural Medicine.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

A pilot study to assess the safety and tolerability of an orally administered natural product derived from hops, called xanthohumol, in humans with Crohn's Disease, in order to identify a biological signature of xanthohumol exposure, and to characterize the role of xanthohumol metabolism by intestinal microorganisms in that signature within adults with Crohn's Disease.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG Xanthohumol

Study Locations (1)

Oregon

  • National University of Natural Medicine - Portland

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2020-10-01
Est. Completion 2025-07-30
Phase Phase 2

What the Registry Record Tells You About NCT04590508

The ClinicalTrials.gov registry entry for NCT04590508 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 205-participant average among 71 other Crohn Disease trials with a reported enrollment target (90% lower). The listed sponsor is National University of Natural Medicine, which has 30 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Crohn Disease appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04590508 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT04590508 about?

NCT04590508 is a clinical study titled "A Phase 2 Clinical Trial: Xanthohumol Metabolism and Signature (XMaS) in Crohn's Disease". A pilot study to assess the safety and tolerability of an orally administered natural product derived from hops, called xanthohumol, in humans with Crohn's Disease, in order to identify a biological signature of xanthohumol exposure, and to characterize the role of xanthohumol metabolism by intestin...

What is the current status of trial NCT04590508?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2020-10-01. Estimated completion is 2025-07-30.

What conditions does trial NCT04590508 study?

This clinical trial studies the following conditions: Crohn Disease.

What interventions are being tested in trial NCT04590508?

The interventions under investigation include: Placebo (OTHER), Xanthohumol (DRUG).

Who is sponsoring clinical trial NCT04590508?

This trial is sponsored by National University of Natural Medicine, which has 30 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04590508 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.