Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare

NCT07145229 · View on ClinicalTrials.gov ↗

Study Summary

A randomized, double-blind, international multicenter, colchicine and placebo-controlled study to evaluate the efficacy and safety of ABP-745 in subjects with acute gout. Efficacy of ABP-745 in reducing pain and swelling compared with standard colchicine treatment and placebo will be evaluated in participants with acute gout. The primary efficacy measurement will be pain score after treatment.

Interventions

  • DRUG Placebo
  • DRUG Colchicine
  • DRUG ABP-745 Dose A
  • DRUG ABP-745 Dose B

Study Locations (20)

New South Wales

  • Emeritus Sydney — Botany
  • Canopy Clinical Research Northern Beaches — Brookvale
  • Novatrials — Kotara
  • Genesis Research Services — Newcastle

Louisiana

  • Northshore Research Associates — Alexandria
  • DelRicht Research — Baton Rouge
  • DelRicht Research — New Orleans

Victoria

  • Emeritus Melbourne — Camberwell
  • Canopy Clinical Research Altona North — North Altona

Arizona

  • Onyx Clinical Research — Peoria

California

  • Exinia Research — La Mesa

Georgia

  • Evergreen Clinical Trial — Norcross

Illinois

  • Bioluminux Clinical Research — Naperville

Iowa

  • Exinia Research — Des Moines

Trial Details

FieldValue
Enrollment Target 380 participants
Start Date 2025-08-26
Est. Completion 2026-06
Phase Phase 2

Sponsor

Atom Therapeutics Co.

1 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07145229

The ClinicalTrials.gov registry entry for NCT07145229 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 380 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Atom Therapeutics Co., which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Gout Flare appearing as the primary indexed condition, and to 4 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07145229 reports 20 study locations spanning 14 distinct geographic areas — top geographies include New South Wales, Louisiana, Victoria. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07145229 about?

NCT07145229 is a clinical study titled "Safety and Efficacy of ABP-745 in Participants With an Acute Gout Flare". A randomized, double-blind, international multicenter, colchicine and placebo-controlled study to evaluate the efficacy and safety of ABP-745 in subjects with acute gout. Efficacy of ABP-745 in reducing pain and swelling compared with standard colchicine treatment and placebo will be evaluated in pa...

What is the current status of trial NCT07145229?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 380 participants. The study started on 2025-08-26. Estimated completion is 2026-06.

What conditions does trial NCT07145229 study?

This clinical trial studies the following conditions: Gout Flare, Acute Gouty Arthritis, Acute Gout Flare, Gout Flares. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07145229?

The interventions under investigation include: Placebo (DRUG), Colchicine (DRUG), ABP-745 Dose A (DRUG), ABP-745 Dose B (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07145229?

This trial is sponsored by Atom Therapeutics Co., which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07145229 being conducted?

This trial has 20 study locations across Arizona, California, Georgia, Illinois, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial