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RECRUITING

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

NCT07143669 · View on ClinicalTrials.gov ↗

Study Summary

This is a multicenter screening study to characterize the prevalence of the KIT D816V mutation in participants with suspected clonal mast cell disease.

Interventions

  • OTHER Screening

Study Locations (14)

California

  • Kaiser Permanente San Diego — San Diego
  • Allergy & Asthma Clinical Research of the Bay Area — Walnut Creek

Alabama

  • AllerVie Clinical Research — Birmingham

Florida

  • Allergy, Asthma, & Immunology Associates of Tampa Bay — Tampa

Georgia

  • Emory University — Atlanta

Illinois

  • Midwest Allergy Sinus Asthma — Normal

Maryland

  • AllerVie Health — Glenn Dale

Missouri

  • Barnes-Jewish West County Hospital — St Louis

Nebraska

  • Somnos Clinical Research — Lincoln

Trial Details

FieldValue
Enrollment Target 450 participants
Start Date 2025-10-17
Est. Completion 2028-10-31

Sponsor

Blueprint Medicines Corporation

9 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07143669

The ClinicalTrials.gov registry entry for NCT07143669 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 450 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Blueprint Medicines Corporation, which has 9 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with KIT D816V Mutation appearing as the primary indexed condition, and to 1 intervention — of which Screening is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07143669 reports 14 study locations spanning 13 distinct geographic areas — top geographies include California, Alabama, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07143669 about?

NCT07143669 is a clinical study titled "Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations". This is a multicenter screening study to characterize the prevalence of the KIT D816V mutation in participants with suspected clonal mast cell disease.

What is the current status of trial NCT07143669?

This trial is currently recruiting. The enrollment target is 450 participants. The study started on 2025-10-17. Estimated completion is 2028-10-31.

What conditions does trial NCT07143669 study?

This clinical trial studies the following conditions: KIT D816V Mutation, Clonal Mast Cell Disease, Suspected KITD816V Mutated Clonal Mast Cell Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07143669?

The interventions under investigation include: Screening (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07143669?

This trial is sponsored by Blueprint Medicines Corporation, which has 9 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07143669 being conducted?

This trial has 14 study locations across Alabama, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial