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NCT07130669 · ClinicalTrials.gov registry record · Phase 1
FACE Phase II (a Stage II Trial)
A Phase 1 study, sponsored by Stanford University.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
NCT07130669: Recruiting Phase 1 study, sponsored by Stanford University.
NCT07130669 is a Phase 1 study that is actively recruiting participants, run by Stanford University. The registered enrollment target is 80 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07130669, a Phase 1 study, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
How to ensure adherence to computerized cognitive training in unsupervised circumstances (e.g., at-home, self-administered) in older adults at risk for Alzheimer's disease (AD) or AD related dementia (AD/ADRD) is understudied. The objective of the R33 study is to test a novel facial expression-based personalization engine (FPE) for monitoring and modulating real-time effective engagement, with an ultimate goal of enhancing long-term adherence in unsupervised cognitive training in older adults at risk for AD/ADRD. Here, Effective engagement is defined as the extent to which someone is actively engaged and performing with significant attention and enjoyment while training, addressing a balance between adherence and cognitive gains/plasticity from the training. Based on previous work, the hypotheses include that (1) mental fatigue revealed in facial expressions will reflect a trainee's degree of effective engagement, which can be modified by modulating task novelty; (2) the proposed FPE will ensure the effective engagement in cognitive training by monitoring trainee facial expressions and modulating training in response, promoting the trainee's long-term adherence to the training and cognitive plasticity. A Stage II intervention efficacy study will be conducted to compare effective engagement and adherence in unsupervised cognitive training between training programs with vs. without FPE in older adults at risk for AD/ADRD. The proposed FPE may assist in monitoring and improving effective engagement and adherence in older adults with unsupervised cognitive training. In the current application, FPE in a cognitive training program called speed of processing training will be tested. However, such FPE may be embedded to any computerized cognitive training in future studies to help address adherence related issues.
Interventions
- BEHAVIORAL Cognitive Remediation
- BEHAVIORAL Cognitive Remediation II
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-10-31 |
| Est. Completion | 2028-08-31 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07130669
The ClinicalTrials.gov registry entry for NCT07130669 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,744 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Cognitive Remediation is the first listed.
NCT07130669 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07130669 about?
NCT07130669 is a clinical study titled "FACE Phase II (a Stage II Trial)". How to ensure adherence to computerized cognitive training in unsupervised circumstances (e.g., at-home, self-administered) in older adults at risk for Alzheimer's disease (AD) or AD related dementia (AD/ADRD) is understudied. The objective of the R33 study is to test a novel facial expression-based...
What is the current status of trial NCT07130669?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2025-10-31. Estimated completion is 2028-08-31.
What interventions are being tested in trial NCT07130669?
The interventions under investigation include: Cognitive Remediation (BEHAVIORAL), Cognitive Remediation II (BEHAVIORAL).
Who is sponsoring clinical trial NCT07130669?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
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