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NCT07128615 · ClinicalTrials.gov registry record · Phase 1

A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA)

A Phase 1 study of Influenza a, sponsored by AstraZeneca.

Active
Registry status
Phase 1
Development phase
405
Enrollment target
14
Study locations

NCT07128615 is a Phase 1 study of Influenza a that is active but no longer recruiting, run by AstraZeneca. The registered enrollment target is 405 participants, below the 2,714-participant average among 10 other Influenza a trials with a reported enrollment target (85% lower). The trial reports 14 study locations across 13 states.

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The verdict

NCT07128615, a Phase 1 study of Influenza a, is active but no longer recruiting, sponsored by AstraZeneca.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
405 participants
Enrollment target
14
Study locations

Study Summary

The purpose of this study is to evaluate the safety and immunogenicity of two investigational vaccines, AZD4117 and AZD5315 to protect against certain strains of avian Influenza A (H5N1 and H7N9 subtypes).

Conditions Studied

Interventions

  • OTHER Placebo
  • BIOLOGICAL AZD4117
  • BIOLOGICAL AZD5315

Study Locations (14)

California

  • Research Site - Long Beach
  • Research Site - Rolling Hills Estates

Florida

  • Research Site - Hialeah

Georgia

  • Research Site - Stockbridge

Illinois

  • Research Site - Chicago

Kansas

  • Research Site - Lenexa

Missouri

  • Research Site - Kansas City

Nebraska

  • Research Site - Omaha

Nevada

  • Research Site - Las Vegas

Trial Details

FieldValue
Enrollment Target 405 participants
Start Date 2025-09-04
Est. Completion 2026-12-29
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT07128615

The ClinicalTrials.gov registry entry for NCT07128615 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 405 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,714-participant average among 10 other Influenza a trials with a reported enrollment target (85% lower). The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Influenza a appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT07128615 reports 14 study locations spanning 13 distinct geographic areas - top geographies include California, Florida, Georgia.

Frequently Asked Questions

What is clinical trial NCT07128615 about?

NCT07128615 is a clinical study titled "A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA)". The purpose of this study is to evaluate the safety and immunogenicity of two investigational vaccines, AZD4117 and AZD5315 to protect against certain strains of avian Influenza A (H5N1 and H7N9 subtypes).

What is the current status of trial NCT07128615?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 405 participants. The study started on 2025-09-04. Estimated completion is 2026-12-29.

What conditions does trial NCT07128615 study?

This clinical trial studies the following conditions: Influenza a.

What interventions are being tested in trial NCT07128615?

The interventions under investigation include: Placebo (OTHER), AZD4117 (BIOLOGICAL), AZD5315 (BIOLOGICAL).

Who is sponsoring clinical trial NCT07128615?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07128615 being conducted?

This trial has 14 study locations across California, Florida, Georgia, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.