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NCT07095556 · ClinicalTrials.gov registry record · NA

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

A NA study of Postoperative Pain Management and Tooth Extraction Site Healing, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
39
Enrollment target
1
Study location

NCT07095556: Recruiting NA study of Postoperative Pain Management and Tooth Extraction Site Healing, sponsored by Medical University of South Carolina.

NCT07095556 is a NA study of Postoperative Pain Management and Tooth Extraction Site Healing that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 39 participants, below the 135-participant average among 7 other Postoperative Pain Management trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07095556, a NA study of Postoperative Pain Management and Tooth Extraction Site Healing, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
39 participants
Enrollment target
1
Study location

Study Summary

The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation. Investigators plan to assess the impact of laser treatment on wound healing by measuring salivary biomarkers, gingival wound size and surveying for the use of pain reduction and patient satisfaction. The intervention group will receive extraction and alveolar ridge preservation with Nd-YAG laser photobiostimulation on days 1, 3, and 7 following extraction and socket preservation, while the control group will receive the standard of care extraction and alveolar ridge preservation without the laser

Primary Outcome

The measurement of inflammatory and anti-inflammatory markers in saliva, IL-1β, IL-6, IL-8, IL-10, IL-12 and TNF secreted during the early stages of wound healing at day 3 and day 7.

Interventions

  • OTHER Low-level laser therapy

Study Locations (1)

South Carolina

  • MUSC College of Dental Medicine, Graduate Periodontics Clinic - Charleston

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2025-11-05
Est. Completion 2027-04-30
Phase NA

What NCT07095556 shows while recruiting

NCT07095556 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 135-participant average among 7 other Postoperative Pain Management trials with a reported enrollment target (71% lower).

The record links to 5 conditions, with Postoperative Pain Management appearing as the primary indexed condition, and to 1 intervention - of which Low-level laser therapy is the first listed.

NCT07095556 reports a single indexed study location in South Carolina.

Frequently Asked Questions

What is clinical trial NCT07095556 about?

NCT07095556 is a clinical study titled "Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva". The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation. Investigators plan to assess the impact of laser treatment on wound healing by measuring salivary bi...

What is the current status of trial NCT07095556?

This trial is currently recruiting. It is a NA study. The enrollment target is 39 participants. The study started on 2025-11-05. Estimated completion is 2027-04-30.

What conditions does trial NCT07095556 study?

This clinical trial studies the following conditions: Postoperative Pain Management, Tooth Extraction Site Healing, Wound Healing and Prevention, Oral Inflammation, Photobiomodulation.

What interventions are being tested in trial NCT07095556?

The interventions under investigation include: Low-level laser therapy (OTHER).

Who is sponsoring clinical trial NCT07095556?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07095556 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT07095556, the US trial registry maintained by the National Library of Medicine. NCT07095556 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.