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NCT07054489 · ClinicalTrials.gov registry record · NA
UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF
A NA study of Heart Failure and Polygenic Score, sponsored by David Lanfear.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT07054489: Recruiting NA study of Heart Failure and Polygenic Score, sponsored by David Lanfear.
NCT07054489 is a NA study of Heart Failure and Polygenic Score that is actively recruiting participants, run by David Lanfear. The registered enrollment target is 10 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07054489, a NA study of Heart Failure and Polygenic Score, is actively recruiting participants, sponsored by David Lanfear.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will use polygenic scores, a tool which describes differences in genetics, to examine effectiveness of beta blocker medication in heart failure patients with ejection fraction of 41-50 percent. The study will also assess beta blockers' effect on the changes in left ventricular end-systolic volume index by MRI.
Primary Outcome
LVESVi, measured in mL per square meter; assessed by cardiac MRI
Conditions Studied
Interventions
- OTHER Beta blocker
Study Locations (1)
Michigan
- Henry Ford Health - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-11 |
| Est. Completion | 2026-11 |
| Phase | NA |
What NCT07054489 shows while recruiting
NCT07054489 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Beta blocker is the first listed.
NCT07054489 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT07054489 about?
NCT07054489 is a clinical study titled "UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF". This study will use polygenic scores, a tool which describes differences in genetics, to examine effectiveness of beta blocker medication in heart failure patients with ejection fraction of 41-50 percent. The study will also assess beta blockers' effect on the changes in left ventricular end-systoli...
What is the current status of trial NCT07054489?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-11. Estimated completion is 2026-11.
What conditions does trial NCT07054489 study?
This clinical trial studies the following conditions: Heart Failure, Polygenic Score.
What interventions are being tested in trial NCT07054489?
The interventions under investigation include: Beta blocker (OTHER).
Who is sponsoring clinical trial NCT07054489?
This trial is sponsored by David Lanfear, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07054489 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07054489's enrollment target sits among peer trials
10 383rd of 397 higher than 7 of 397 other Heart Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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