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NCT07053033 · ClinicalTrials.gov registry record · Phase 2
Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)
A Phase 2 study of Brain Metastases, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 155
- Enrollment target
- 1
- Study location
NCT07053033: Recruiting Phase 2 study of Brain Metastases, sponsored by M.D. Anderson Cancer Center.
NCT07053033 is a Phase 2 study of Brain Metastases that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 155 participants, below the 211-participant average among 67 other Brain Metastases trials with a reported enrollment target (27% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07053033, a Phase 2 study of Brain Metastases, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 155 participants
- Enrollment target
- 1
- Study location
Study Summary
standard paradigm for management of patients who present with concern for recurrence of brain metastases following initial stereotactic radiosurgery (SRS).
Primary Outcome
Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0
Conditions Studied
Interventions
- PROCEDURE Surgery
- PROCEDURE LITT
Study Locations (1)
Texas
- The University of Texas M. D. Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 155 participants |
| Start Date | 2026-01-01 |
| Est. Completion | 2028-12-30 |
| Phase | Phase 2 |
What NCT07053033 shows while recruiting
NCT07053033 is an interventional study that assigns participants to a tested intervention. The registered 155 participants enrollment target is mid-sized for trials with a published cap, below the 211-participant average among 67 other Brain Metastases trials with a reported enrollment target (27% lower).
The record links to 1 condition, with Brain Metastases appearing as the primary indexed condition, and to 2 interventions - of which Surgery is the first listed.
NCT07053033 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07053033 about?
NCT07053033 is a clinical study titled "Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)". standard paradigm for management of patients who present with concern for recurrence of brain metastases following initial stereotactic radiosurgery (SRS).
What is the current status of trial NCT07053033?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 155 participants. The study started on 2026-01-01. Estimated completion is 2028-12-30.
What conditions does trial NCT07053033 study?
This clinical trial studies the following conditions: Brain Metastases.
What interventions are being tested in trial NCT07053033?
The interventions under investigation include: Surgery (PROCEDURE), LITT (PROCEDURE).
Who is sponsoring clinical trial NCT07053033?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07053033 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Metastases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07053033's enrollment target sits among peer trials
155 9th of 67 higher than 59 of 67 other Brain Metastases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Metastases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active
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