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NCT07027306 · ClinicalTrials.gov registry record
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
A clinical trial of Osteoporosis and Osteoporotic Fractures, sponsored by AO Foundation, AO Spine.
- Recruiting
- Registry status
- 648
- Enrollment target
- 15
- Study locations
NCT07027306: Recruiting study of Osteoporosis and Osteoporotic Fractures, sponsored by AO Foundation, AO Spine.
NCT07027306 is a study of Osteoporosis and Osteoporotic Fractures that is actively recruiting participants, run by AO Foundation, AO Spine. The registered enrollment target is 648 participants, below the 1,538-participant average among 84 other Osteoporosis trials with a reported enrollment target (58% lower). The trial reports 15 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07027306, a study of Osteoporosis and Osteoporotic Fractures, is actively recruiting participants, sponsored by AO Foundation, AO Spine.
- RECRUITING
- Registry status
- 648 participants
- Enrollment target
- 15
- Study locations
Study Summary
This is an international multicenter prospective observational study. Patients with radiologically confirmed, symptomatic, single- or multilevel contiguous TL (from T1 to L5) fractures as a result of primary osteoporosis will be recruited from participating clinics/hospitals (ie, study sites). Fractures included are insufficiency fractures (confirmed by magnetic resonance imaging \[MRI\]) and traumatic fractures (low-energy trauma, confirmed by computed tomography \[CT\] or MRI).
Primary Outcome
Determination in patients with symptomatic osteoporotic TL fractures whether an initial treatment adhering to the OF score recommendations (the Accordance group) generates better short-term patient outcomes regarding time to return to mobility level before injury or symptom onset within 3 months after treatment compared to an initial treatment decision not adhering to the OF score recommendations (the Discordance group). The primary outcome of the study is return to the mobility level. Patients
Conditions Studied
Interventions
- PROCEDURE Posterior stabilization (pedicle screws)
Study Locations (15)
Other
- Sanatorio Güemes - Buenos Aires
- Cajuru University Hospital - Curitiba
- Department of Orthopedic Surgery, Clinica Alemana de Santiago - Santiago
- Orthopaedic Department, Assiut University Hospitals, Faculty of Medicine - Asyut
- Tampere University Hospital - Tampere
- Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien - Erlangen
- PGIMER - Postgraduate Institute of Medical Education and Research - Chandigarh
- Dokkyo Medical University Hospital - Tochigi
- Island Hospital Spine Centre - George Town
- Spiatlul Clinic De Urgenta, "Profesor Doctor Nicolae Oblu" - Iași
- Security Force Hospital - Riyāḑ
- Spital Emmental - Orthopädie Sonnenhof - Burgdorf
- King's College Hospital - London
California
- University of California San Francisco (USCF) Department of Orthopaedic Surgery - San Francisco
Pennsylvania
- Thomas Jefferson University Hospital - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 648 participants |
| Start Date | 2026-03-10 |
| Est. Completion | 2030-12-01 |
What NCT07027306 shows while recruiting
NCT07027306 is an observational study that tracks outcomes without assigning an intervention. The registered 648 participants enrollment target is mid-sized for trials with a published cap, below the 1,538-participant average among 84 other Osteoporosis trials with a reported enrollment target (58% lower).
The record links to 2 conditions, with Osteoporosis appearing as the primary indexed condition, and to 1 intervention - of which Posterior stabilization (pedicle screws) is the first listed.
NCT07027306 lists 15 locations in 3 states (Other, California, Pennsylvania).
Frequently Asked Questions
What is clinical trial NCT07027306 about?
NCT07027306 is a clinical study titled "The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures". This is an international multicenter prospective observational study. Patients with radiologically confirmed, symptomatic, single- or multilevel contiguous TL (from T1 to L5) fractures as a result of primary osteoporosis will be recruited from participating clinics/hospitals (ie, study sites). Fract...
What is the current status of trial NCT07027306?
This trial is currently recruiting. The enrollment target is 648 participants. The study started on 2026-03-10. Estimated completion is 2030-12-01.
What conditions does trial NCT07027306 study?
This clinical trial studies the following conditions: Osteoporosis, Osteoporotic Fractures.
What interventions are being tested in trial NCT07027306?
The interventions under investigation include: Posterior stabilization (pedicle screws) (PROCEDURE).
Who is sponsoring clinical trial NCT07027306?
This trial is sponsored by AO Foundation, AO Spine, which has 9 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07027306 being conducted?
This trial has 15 study locations across California, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoporosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07027306's enrollment target sits among peer trials
648 16th of 84 higher than 69 of 84 other Osteoporosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoporosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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