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NCT06990841 · ClinicalTrials.gov registry record · NA
Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development
A NA study of Sperm DNA Fragmentation and DNA Damage, sponsored by Richard Kordus, PhD, HCLD (ABB).
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT06990841 is a NA study of Sperm DNA Fragmentation and DNA Damage that is actively recruiting participants, run by Richard Kordus, PhD, HCLD (ABB). The registered enrollment target is 50 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06990841, a NA study of Sperm DNA Fragmentation and DNA Damage, is actively recruiting participants, sponsored by Richard Kordus, PhD, HCLD (ABB).
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if the LensHooke CA0 device lowers DNA fragmentation in sperm samples compared to a gradient/swim-up technique. The main questions it aims to answer are: 1. Does the LensHooke® CA0 device reduce DNA fragmentation compared to the gradient/swim-up technique? 2. Does the LensHooke® CA0 device improve concentration, motility, and morphology compared to the gradient/swim-up technique? 3. Is sibling embryo fertilization and development the same? 4. Are pregnancy rates different between the 2 groups? 1 semen sample will be split between the 2 treatment techniques. Half of the partner's egg cohort will be injected via intra-cytoplasmic sperm using sperm processed by one technique and the other half of the cohort will be injected by the sperm processed by the other technique. Both methods will look at DNA fragmentation, concentration, motility, and morphology of the sperm. Both methods will be compared in the resulting embryos looking at fertilization, embryo development and pregnancy rates.
Conditions Studied
Interventions
- DEVICE sperm separation device
Study Locations (1)
South Carolina
- Prisma Health-Upstate Fertility Center of the Caroliinas - Greenville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2025-08-11 |
| Est. Completion | 2026-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06990841
The ClinicalTrials.gov registry entry for NCT06990841 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Richard Kordus, PhD, HCLD (ABB), which has 1 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Sperm DNA Fragmentation appearing as the primary indexed condition, and to 1 intervention - of which sperm separation device is the first listed.
NCT06990841 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.
Frequently Asked Questions
What is clinical trial NCT06990841 about?
NCT06990841 is a clinical study titled "Comparison of Two Different Sperm Processing Methods and Their Effects on Sperm DNA Fragmentation and Embryo Development". The goal of this clinical trial is to learn if the LensHooke CA0 device lowers DNA fragmentation in sperm samples compared to a gradient/swim-up technique. The main questions it aims to answer are: 1. Does the LensHooke® CA0 device reduce DNA fragmentation compared to the gradient/swim-up techniqu...
What is the current status of trial NCT06990841?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2025-08-11. Estimated completion is 2026-12.
What conditions does trial NCT06990841 study?
This clinical trial studies the following conditions: Sperm DNA Fragmentation, DNA Damage, DNA Strand Breaks.
What interventions are being tested in trial NCT06990841?
The interventions under investigation include: sperm separation device (DEVICE).
Who is sponsoring clinical trial NCT06990841?
This trial is sponsored by Richard Kordus, PhD, HCLD (ABB), which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06990841 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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