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NCT06983743 · ClinicalTrials.gov registry record · Phase 1
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
A Phase 1 study of Metastatic Solid Tumors, sponsored by Erasca.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 200
- Enrollment target
- 5
- Study locations
NCT06983743: Recruiting Phase 1 study of Metastatic Solid Tumors, sponsored by Erasca.
NCT06983743 is a Phase 1 study of Metastatic Solid Tumors that is actively recruiting participants, run by Erasca. The registered enrollment target is 200 participants, roughly in line with the 196-participant average among 20 other Metastatic Solid Tumors trials with a reported enrollment target. The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06983743, a Phase 1 study of Metastatic Solid Tumors, is actively recruiting participants, sponsored by Erasca.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 200 participants
- Enrollment target
- 5
- Study locations
Study Summary
The main purpose of the study is to assess whether the study drug, ERAS-0015, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with certain RAS mutations. ERAS-0015 will be given alone or in combination with other treatments.
Primary Outcome
Based on toxicities observed
Conditions Studied
Interventions
- DRUG ERAS-0015
- DRUG ERAS-0015 in combination
Study Locations (5)
Texas
- The University of Texas MD Anderson Cancer Center - Houston
- University of Texas at Tyler - Tyler
Florida
- Florida Cancer Specalists - Sarasota
New York
- Memorial Sloan Kettering Cancer Center - New York
Virginia
- NEXT Virginia - Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2025-06-05 |
| Est. Completion | 2028-12-01 |
| Phase | Phase 1 |
What NCT06983743 shows while recruiting
NCT06983743 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 196-participant average among 20 other Metastatic Solid Tumors trials with a reported enrollment target.
The record links to 1 condition, with Metastatic Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which ERAS-0015 is the first listed.
NCT06983743 lists 5 locations in 4 states (Texas, Florida, New York).
Frequently Asked Questions
What is clinical trial NCT06983743 about?
NCT06983743 is a clinical study titled "A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors". The main purpose of the study is to assess whether the study drug, ERAS-0015, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with certain RAS mutations. ERAS-0015 will be given alone or in combination with other treatments.
What is the current status of trial NCT06983743?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 200 participants. The study started on 2025-06-05. Estimated completion is 2028-12-01.
What conditions does trial NCT06983743 study?
This clinical trial studies the following conditions: Metastatic Solid Tumors.
What interventions are being tested in trial NCT06983743?
The interventions under investigation include: ERAS-0015 (DRUG), ERAS-0015 in combination (DRUG).
Who is sponsoring clinical trial NCT06983743?
This trial is sponsored by Erasca, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06983743 being conducted?
This trial has 5 study locations across Florida, New York, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06983743's enrollment target sits among peer trials
200 8th of 20 higher than 11 of 20 other Metastatic Solid Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Solid Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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