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NCT06983730 · ClinicalTrials.gov registry record · Early Phase 1

The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response

A Early Phase 1 study of Healthy Volunteer Study and Kidney Dysfunction, sponsored by Beth Israel Deaconess Medical Center.

Recruiting
Registry status
Early Phase 1
Development phase
28
Enrollment target
2
Study locations

NCT06983730: Recruiting Early Phase 1 study of Healthy Volunteer Study and Kidney Dysfunction, sponsored by Beth Israel Deaconess Medical Center.

NCT06983730 is a Early Phase 1 study of Healthy Volunteer Study and Kidney Dysfunction that is actively recruiting participants, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 28 participants, below the 33-participant average among 9 other Healthy Volunteer Study trials with a reported enrollment target (15% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06983730, a Early Phase 1 study of Healthy Volunteer Study and Kidney Dysfunction, is actively recruiting participants, sponsored by Beth Israel Deaconess Medical Center.

RECRUITING
Registry status
Early Phase 1
Development phase
28 participants
Enrollment target
2
Study locations

Study Summary

The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers. The main questions it aims to answer are: * How do the chemicals produced by the body change under conditions of higher versus lower heat stress? * What role does a specific area of the body's metabolism, known as NAD+ metabolism, play in the body's response to heat stress, and can this response be modified by taking vitamin B3?

Primary Outcome

Marker of stress and injury in the kidney

Interventions

  • DIETARY_SUPPLEMENT Vitamin B3

Study Locations (2)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston
  • Boston University - Boston

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2026-01-26
Est. Completion 2028-06
Phase Early Phase 1

What NCT06983730 shows while recruiting

NCT06983730 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 33-participant average among 9 other Healthy Volunteer Study trials with a reported enrollment target (15% lower).

The record links to 3 conditions, with Healthy Volunteer Study appearing as the primary indexed condition, and to 1 intervention - of which Vitamin B3 is the first listed.

NCT06983730 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT06983730 about?

NCT06983730 is a clinical study titled "The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response". The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers. The main questions it aims to answer are: * How do the chemicals produced by the body change under conditions of higher versus lower heat stress? * What role does ...

What is the current status of trial NCT06983730?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 28 participants. The study started on 2026-01-26. Estimated completion is 2028-06.

What conditions does trial NCT06983730 study?

This clinical trial studies the following conditions: Healthy Volunteer Study, Kidney Dysfunction, Heat Strain.

What interventions are being tested in trial NCT06983730?

The interventions under investigation include: Vitamin B3 (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT06983730?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06983730 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy Volunteer Study

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06983730's enrollment target sits among peer trials

28 5th of 9 higher than 4 of 9 other Healthy Volunteer Study trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy Volunteer Study trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06983730, the US trial registry maintained by the National Library of Medicine. NCT06983730 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.