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NCT06966024 · ClinicalTrials.gov registry record · Phase 1
Study of DCC-2812 in Participants With Advanced Genitourinary Cancers
A Phase 1 study of Renal Cell Carcinoma and Urothelial Carcinoma, sponsored by Deciphera Pharmaceuticals.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 60
- Enrollment target
- 3
- Study locations
NCT06966024: Recruiting Phase 1 study of Renal Cell Carcinoma and Urothelial Carcinoma, sponsored by Deciphera Pharmaceuticals.
NCT06966024 is a Phase 1 study of Renal Cell Carcinoma and Urothelial Carcinoma that is actively recruiting participants, run by Deciphera Pharmaceuticals. The registered enrollment target is 60 participants, below the 242-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (75% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06966024, a Phase 1 study of Renal Cell Carcinoma and Urothelial Carcinoma, is actively recruiting participants, sponsored by Deciphera Pharmaceuticals.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a multicenter clinical trial to evaluate the safety and preliminary activity of the selective general control nonderepressible 2 (GCN2) activator DCC-2812 as monotherapy in advanced/metastatic renal cell carcinoma (RCC), urothelial carcinoma, and castration-resistant prostate cancer.
Conditions Studied
Interventions
- DRUG DCC-2812
Study Locations (3)
Texas
- NEXT Oncology, Austin - Austin
- NEXT Oncology, San Antonio - San Antonio
Massachusetts
- Dana-Farber Cancer Institute - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-08-27 |
| Est. Completion | 2029-02 |
| Phase | Phase 1 |
What NCT06966024 shows while recruiting
NCT06966024 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 242-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (75% lower).
The record links to 3 conditions, with Renal Cell Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which DCC-2812 is the first listed.
NCT06966024 reports a single indexed study location in Texas, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06966024 about?
NCT06966024 is a clinical study titled "Study of DCC-2812 in Participants With Advanced Genitourinary Cancers". This is a multicenter clinical trial to evaluate the safety and preliminary activity of the selective general control nonderepressible 2 (GCN2) activator DCC-2812 as monotherapy in advanced/metastatic renal cell carcinoma (RCC), urothelial carcinoma, and castration-resistant prostate cancer.
What is the current status of trial NCT06966024?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2025-08-27. Estimated completion is 2029-02.
What conditions does trial NCT06966024 study?
This clinical trial studies the following conditions: Renal Cell Carcinoma, Urothelial Carcinoma, Castration-resistant Prostate Cancer.
What interventions are being tested in trial NCT06966024?
The interventions under investigation include: DCC-2812 (DRUG).
Who is sponsoring clinical trial NCT06966024?
This trial is sponsored by Deciphera Pharmaceuticals, which has 21 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06966024 being conducted?
This trial has 3 study locations across Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06966024's enrollment target sits among peer trials
60 70th of 121 higher than 48 of 121 other Renal Cell Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Renal Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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