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ACTIVE NOT RECRUITING Phase 3

A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis

NCT06934226 · View on ClinicalTrials.gov ↗

Study Summary

The main purpose of this study is to assess how well JNJ-77242113 works when compared to placebo and ustekinumab in participants with moderate to severe plaque psoriasis.

Conditions Studied

Interventions

  • DRUG Ustekinumab
  • DRUG JNJ-77242113
  • DRUG Matching Placebo to JNJ-77242113
  • DRUG Matching Placebo to Ustekinumab

Study Locations (20)

California

  • California Dermatology & Clinical Research Institute — Encinitas
  • T Joseph Raoof Md Inc — Encino
  • First OC Dermatology — Fountain Valley
  • Dermatologist Medical Group of North County, Inc. — Oceanside
  • NorCal Clinical Research — Rocklin
  • Integrative Skin Science and Research — Sacramento
  • MedDerm Associates — San Diego
  • Southern California Dermatology — Santa Ana
  • Olive View-UCLA Education & Research Institute — Sylmar

Florida

  • Driven Research LLC — Coral Gables
  • Bioclinical Research Alliance Inc. — Miami
  • Renstar Medical Research — Ocala
  • Forcare Clinical Research Inc — Tampa

Alabama

  • Cahaba Research Inc — Birmingham

Connecticut

  • University of Conn Health Center — Farmington

Georgia

  • Hamilton Research LLC — Alpharetta

Illinois

  • Northshore Medical Group — Skokie

Indiana

  • Indiana Clinical Trial Center — Plainfield

Iowa

  • University of Iowa — Iowa City

Trial Details

FieldValue
Enrollment Target 752 participants
Start Date 2025-04-15
Est. Completion 2027-08-20
Phase Phase 3

Sponsor

Janssen Research & Development

442 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06934226

The ClinicalTrials.gov registry entry for NCT06934226 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 752 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Plaque Psoriasis appearing as the primary indexed condition, and to 4 interventions — of which Ustekinumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06934226 reports 20 study locations spanning 9 distinct geographic areas — top geographies include California, Florida, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06934226 about?

NCT06934226 is a clinical study titled "A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis". The main purpose of this study is to assess how well JNJ-77242113 works when compared to placebo and ustekinumab in participants with moderate to severe plaque psoriasis.

What is the current status of trial NCT06934226?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 752 participants. The study started on 2025-04-15. Estimated completion is 2027-08-20.

What conditions does trial NCT06934226 study?

This clinical trial studies the following conditions: Plaque Psoriasis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06934226?

The interventions under investigation include: Ustekinumab (DRUG), JNJ-77242113 (DRUG), Matching Placebo to JNJ-77242113 (DRUG), Matching Placebo to Ustekinumab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06934226?

This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06934226 being conducted?

This trial has 20 study locations across Alabama, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial