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RECRUITING Phase 1

A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors.

NCT06907043 · View on ClinicalTrials.gov ↗

Study Summary

This study will evaluate the safety, tolerability, and preliminary efficacy of EIK1004 (IMP1707) in participants with recurrent advanced/metastatic breast cancer, ovarian cancer, metastatic castrate resistant prostate cancer (mCRPC) and pancreatic cancer with deleterious/suspected deleterious mutations of select homologous recombination repair (HRR) genes. Condition or disease Intervention/treatment Phase Advanced Solid Tumors Drug: EIK1004 (IMP1707) Phase 1/Phase 2

Conditions Studied

Interventions

  • DRUG EIK1004-001 (IMP1707-001)

Study Locations (10)

Texas

  • MD Anderson — Houston
  • NEXT Oncology — San Antonio

Colorado

  • Sarah Cannon Research Institute at HealthOne — Denver

Florida

  • Florida Cancer Center — Lake Mary

Massachusetts

  • Beth Israel Deaconess Medical Center — Boston

Virginia

  • NEXT Virginia — Fairfax

Victoria

  • PASO Medical — Frankston

Chongqing Municipality

  • Chongqing University Cancer Hospital — Chongqing

Shandong

  • Cancer Hospital of Shandong First Medical University(Shandong Cancer Institute, Shandong Cancer Hospital) — Jinan

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2025-04-30
Est. Completion 2028-12
Phase Phase 1

Sponsor

Eikon Therapeutics

37 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06907043

The ClinicalTrials.gov registry entry for NCT06907043 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eikon Therapeutics, which has 37 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention — of which EIK1004-001 (IMP1707-001) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06907043 reports 10 study locations spanning 9 distinct geographic areas — top geographies include Texas, Colorado, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06907043 about?

NCT06907043 is a clinical study titled "A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors.". This study will evaluate the safety, tolerability, and preliminary efficacy of EIK1004 (IMP1707) in participants with recurrent advanced/metastatic breast cancer, ovarian cancer, metastatic castrate resistant prostate cancer (mCRPC) and pancreatic cancer with deleterious/suspected deleterious mutati...

What is the current status of trial NCT06907043?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 130 participants. The study started on 2025-04-30. Estimated completion is 2028-12.

What conditions does trial NCT06907043 study?

This clinical trial studies the following conditions: Advanced Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06907043?

The interventions under investigation include: EIK1004-001 (IMP1707-001) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06907043?

This trial is sponsored by Eikon Therapeutics, which has 37 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06907043 being conducted?

This trial has 10 study locations across Colorado, Florida, Massachusetts, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial