Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

Study of Once-Daily Oral RGT001-075 Compared With Placebo in Adults With Obesity or Are Overweight With Weight-Related Health Conditions

NCT06867718 · View on ClinicalTrials.gov ↗

Study Summary

This is a phase 2, 36-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of RGT001-075 in adults who are obese (BMI ≥30 kg/m²) or who are overweight (BMI ≥27 kg/m²) with at least one weight-related comorbidity. RGT001-075 or matching placebo will be administered once daily.

Conditions Studied

Interventions

  • DRUG Placebo Comparator
  • DRUG RGT001-075

Study Locations (20)

Florida

  • Angels Clinical Research — Doral
  • Optimal Research — Melbourne
  • Angels Clinical Research — Miami
  • Palm Springs Community Health Center — Miami Lakes
  • Synexus Clinical Research — The Villages

Georgia

  • Javara-Privia Medical Group, Georgia LLC — Savannah
  • Javara-Privia Medical Group, Georgia, LLC — Thomasville

Indiana

  • Synexus Clinical Research — Evansville
  • Velocity Clinical Research — Valparaiso

Minnesota

  • Mankato Clinic-East Main Street-Javara — Mankato
  • Synexus Clinical Research — Richfield

Alabama

  • Alliance for Multispecialty Research, LLC — Mobile

Arizona

  • Synexus Clinical Research — Phoenix

California

  • Velocity Clinical Research — Huntington Park

Kentucky

  • Alliance for Multispecialty Research, LLC — Lexington

Trial Details

FieldValue
Enrollment Target 236 participants
Start Date 2025-01-24
Est. Completion 2025-12-12
Phase Phase 2

Sponsor

Regor Pharmaceuticals

2 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06867718

The ClinicalTrials.gov registry entry for NCT06867718 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 236 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Regor Pharmaceuticals, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Obesity or Overweight appearing as the primary indexed condition, and to 2 interventions — of which Placebo Comparator is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06867718 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Florida, Georgia, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06867718 about?

NCT06867718 is a clinical study titled "Study of Once-Daily Oral RGT001-075 Compared With Placebo in Adults With Obesity or Are Overweight With Weight-Related Health Conditions". This is a phase 2, 36-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of RGT001-075 in adults who are obese (BMI ≥30 kg/m²) or who are overweight (BMI ≥27 kg/m²) wit...

What is the current status of trial NCT06867718?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 236 participants. The study started on 2025-01-24. Estimated completion is 2025-12-12.

What conditions does trial NCT06867718 study?

This clinical trial studies the following conditions: Obesity or Overweight. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06867718?

The interventions under investigation include: Placebo Comparator (DRUG), RGT001-075 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06867718?

This trial is sponsored by Regor Pharmaceuticals, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06867718 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial