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RECRUITING NA

WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)

NCT06861790 · View on ClinicalTrials.gov ↗

Study Summary

The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.

Conditions Studied

Interventions

  • BEHAVIORAL tVNS
  • PROCEDURE Complete Vagotomy
  • PROCEDURE Anterior Vagotomy

Study Locations (1)

Florida

  • University of Florida - College of Public Health and Health Professions — Gainesville

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2025-11-10
Est. Completion 2027-12
Phase NA

Sponsor

University of Florida

1,066 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06861790

The ClinicalTrials.gov registry entry for NCT06861790 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,066 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Diabetes appearing as the primary indexed condition, and to 3 interventions — of which tVNS is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06861790 reports 1 study location spanning 1 distinct geographic area — top geographies include Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06861790 about?

NCT06861790 is a clinical study titled "WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)". The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves...

What is the current status of trial NCT06861790?

This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-11-10. Estimated completion is 2027-12.

What conditions does trial NCT06861790 study?

This clinical trial studies the following conditions: Diabetes, Weight Loss. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06861790?

The interventions under investigation include: tVNS (BEHAVIORAL), Complete Vagotomy (PROCEDURE), Anterior Vagotomy (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06861790?

This trial is sponsored by University of Florida, which has 1,066 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06861790 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial