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NCT06861790 · ClinicalTrials.gov registry record · NA
WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
A NA study of Diabetes and Weight Loss, sponsored by University of Florida.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06861790: Recruiting NA study of Diabetes and Weight Loss, sponsored by University of Florida.
NCT06861790 is a NA study of Diabetes and Weight Loss that is actively recruiting participants, run by University of Florida. The registered enrollment target is 120 participants, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06861790, a NA study of Diabetes and Weight Loss, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.
Primary Outcome
Utilizing MRS the study seeks to understand changes in brain inflammation between the groups
Conditions Studied
Interventions
- BEHAVIORAL tVNS
- PROCEDURE Complete Vagotomy
- PROCEDURE Anterior Vagotomy
Study Locations (1)
Florida
- University of Florida - College of Public Health and Health Professions - Gainesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-11-10 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT06861790 shows while recruiting
NCT06861790 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 3,028-participant average among 338 other Diabetes trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Diabetes appearing as the primary indexed condition, and to 3 interventions - of which tVNS is the first listed.
NCT06861790 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06861790 about?
NCT06861790 is a clinical study titled "WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)". The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves...
What is the current status of trial NCT06861790?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-11-10. Estimated completion is 2027-12.
What conditions does trial NCT06861790 study?
This clinical trial studies the following conditions: Diabetes, Weight Loss.
What interventions are being tested in trial NCT06861790?
The interventions under investigation include: tVNS (BEHAVIORAL), Complete Vagotomy (PROCEDURE), Anterior Vagotomy (PROCEDURE).
Who is sponsoring clinical trial NCT06861790?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06861790 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06861790's enrollment target sits among peer trials
120 182nd of 338 higher than 156 of 338 other Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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