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NCT06858319 · ClinicalTrials.gov registry record · Phase 3
Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.
A Phase 3 study of Kidney Diseases and Glomerular Disease, sponsored by Novartis Pharmaceuticals.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 220
- Enrollment target
- 6
- Study locations
NCT06858319: Recruiting Phase 3 study of Kidney Diseases and Glomerular Disease, sponsored by Novartis Pharmaceuticals.
NCT06858319 is a Phase 3 study of Kidney Diseases and Glomerular Disease that is actively recruiting participants, run by Novartis Pharmaceuticals. The registered enrollment target is 220 participants, below the 1,780-participant average among 38 other Kidney Diseases trials with a reported enrollment target (88% lower). The trial reports 6 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06858319, a Phase 3 study of Kidney Diseases and Glomerular Disease, is actively recruiting participants, sponsored by Novartis Pharmaceuticals.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 220 participants
- Enrollment target
- 6
- Study locations
Study Summary
The purpose of this study is to determine if zigakibart is safe and effective for long-term use in patients with immunoglobulin A nephropathy (IgAN). This is an extension study for patients who have already completed an another zigakibart study.
Primary Outcome
Number of participants with adverse events will be provided.
Conditions Studied
Interventions
- DRUG zigakibart
Study Locations (6)
Colorado
- Colorado Kidney Care Nephrology - Denver
New York
- NY Nephrology - Clifton Park
Tennessee
- Knoxville Kidney Center Pllc - Brentwood
Buenos Aires F.D.
- Novartis Investigative Site - Buenos Aires
Other
- Novartis Investigative Site - Santa Fe
Korea
- Novartis Investigative Site - Seoul
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 220 participants |
| Start Date | 2025-07-28 |
| Est. Completion | 2031-06-25 |
| Phase | Phase 3 |
What NCT06858319 shows while recruiting
NCT06858319 is an interventional study that assigns participants to a tested intervention. The registered 220 participants enrollment target is mid-sized for trials with a published cap, below the 1,780-participant average among 38 other Kidney Diseases trials with a reported enrollment target (88% lower).
The record links to 8 conditions, with Kidney Diseases appearing as the primary indexed condition, and to 1 intervention - of which zigakibart is the first listed.
NCT06858319 lists 6 locations in 6 states (Colorado, New York, Tennessee).
Frequently Asked Questions
What is clinical trial NCT06858319 about?
NCT06858319 is a clinical study titled "Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.". The purpose of this study is to determine if zigakibart is safe and effective for long-term use in patients with immunoglobulin A nephropathy (IgAN). This is an extension study for patients who have already completed an another zigakibart study.
What is the current status of trial NCT06858319?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 220 participants. The study started on 2025-07-28. Estimated completion is 2031-06-25.
What conditions does trial NCT06858319 study?
This clinical trial studies the following conditions: Kidney Diseases, Glomerular Disease, Kidney Diseases, Chronic, Glomerulonephritis, IGA, Glomerulopathy.
What interventions are being tested in trial NCT06858319?
The interventions under investigation include: zigakibart (DRUG).
Who is sponsoring clinical trial NCT06858319?
This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06858319 being conducted?
This trial has 6 study locations across Colorado, New York, Tennessee, Buenos Aires F.D., Korea. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Kidney Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06858319's enrollment target sits among peer trials
220 14th of 38 higher than 25 of 38 other Kidney Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Kidney Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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