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ACTIVE NOT RECRUITING Phase 3

Savolitinib vs. Sunitinib in MET-driven PRCC.

NCT03091192 · View on ClinicalTrials.gov ↗

Study Summary

This study is designed for patients diagnosed with MET-driven, unresectable and locally advanced or metastatic Papillary Renal Cell Carcinoma. The purpose of this study is to see if an investigational new anti-cancer medication, savolitinib, is effective in treating patients with MET-driven PRCC, how it compares with another medication frequently used to treat this disease called sunitinib, and what side effects it might cause.

Interventions

  • DRUG Sunitinib
  • DRUG Savolitinib

Study Locations (20)

Other

  • Research Site — Barretos
  • Research Site — Curitiba
  • Research Site — Passo Fundo
  • Research Site — Pelotas
  • Research Site — Porto Alegre
  • Research Site — Porto Alegre
  • Research Site — Porto Alegre
  • Research Site — Rio de Janeiro
  • Research Site — São José do Rio Preto
  • Research Site — São Paulo
  • Research Site — São Paulo
  • Research Site — Bordeaux

California

  • Research Site — La Jolla

Georgia

  • Research Site — Atlanta

Illinois

  • Research Site — Chicago

Iowa

  • Research Site — Iowa City

Massachusetts

  • Research Site — Boston

Missouri

  • Research Site — Kansas City

New York

  • Research Site — New York

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2017-07-25
Est. Completion 2026-12-31
Phase Phase 3

Sponsor

AstraZeneca

1,053 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03091192

The ClinicalTrials.gov registry entry for NCT03091192 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,053 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 8 conditions, with Kidney Diseases appearing as the primary indexed condition, and to 2 interventions — of which Sunitinib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03091192 reports 20 study locations spanning 9 distinct geographic areas — top geographies include Other, California, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03091192 about?

NCT03091192 is a clinical study titled "Savolitinib vs. Sunitinib in MET-driven PRCC.". This study is designed for patients diagnosed with MET-driven, unresectable and locally advanced or metastatic Papillary Renal Cell Carcinoma. The purpose of this study is to see if an investigational new anti-cancer medication, savolitinib, is effective in treating patients with MET-driven PRCC, ho...

What is the current status of trial NCT03091192?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 60 participants. The study started on 2017-07-25. Estimated completion is 2026-12-31.

What conditions does trial NCT03091192 study?

This clinical trial studies the following conditions: Kidney Diseases, Carcinoma, Renal Cell, Carcinoma, Neoplasms by Site, Kidney Neoplasms. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03091192?

The interventions under investigation include: Sunitinib (DRUG), Savolitinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03091192?

This trial is sponsored by AstraZeneca, which has 1,053 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03091192 being conducted?

This trial has 20 study locations across California, Georgia, Illinois, Iowa, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial