Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06830876 · ClinicalTrials.gov registry record · NA
Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA
A NA study of Amputation, sponsored by Sara Peterson-Snyder.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06830876: Recruiting NA study of Amputation, sponsored by Sara Peterson-Snyder.
NCT06830876 is a NA study of Amputation that is actively recruiting participants, run by Sara Peterson-Snyder. The registered enrollment target is 20 participants, below the 133-participant average among 65 other Amputation trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06830876, a NA study of Amputation, is actively recruiting participants, sponsored by Sara Peterson-Snyder.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposal aims to investigate a non-invasive, cost-effective method for rebuilding muscle mass in individuals with transtibial limb loss. Maintaining a healthy, pain-free residual limb is a primary concern for prosthesis users. Amputees commonly experience muscle deficits leading to mobility issues, poor prosthetic fit, and chronic pain. Neuromuscular electrical stimulation (NMES) is a potential intervention that activates muscles with low-level electrical stimulation, improving strength, function, and reducing pain. The study seeks to understand NMES's effects on muscle parameters and pain to develop evidence-based interventions for amputees. Twenty participants with transtibial amputations will undergo an 8-week NMES training program. Ultrasound imaging will assess muscle thickness, cross-sectional area, and composition changes. The study aims to enhance mobility, prosthetic fit, and overall well-being of amputees, addressing challenges and reducing healthcare burdens.
Primary Outcome
Compared to baseline, amputees' residual limb will show changes in Muscle Thickness (MT) measured in centimeters (cm) of the vastus medialis oblique (VMO), Tibialis Anterior (TA) and gastrocnemius muscles (GM) post-NMES intervention.
Conditions Studied
Interventions
- DEVICE Chattanooga Continuum Device
Study Locations (1)
Pennsylvania
- Cranberry Township Building - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-12-10 |
| Est. Completion | 2025-12-30 |
| Phase | NA |
What NCT06830876 shows while recruiting
NCT06830876 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 65 other Amputation trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Amputation appearing as the primary indexed condition, and to 1 intervention - of which Chattanooga Continuum Device is the first listed.
NCT06830876 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06830876 about?
NCT06830876 is a clinical study titled "Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA". The proposal aims to investigate a non-invasive, cost-effective method for rebuilding muscle mass in individuals with transtibial limb loss. Maintaining a healthy, pain-free residual limb is a primary concern for prosthesis users. Amputees commonly experience muscle deficits leading to mobility iss...
What is the current status of trial NCT06830876?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-12-10. Estimated completion is 2025-12-30.
What conditions does trial NCT06830876 study?
This clinical trial studies the following conditions: Amputation.
What interventions are being tested in trial NCT06830876?
The interventions under investigation include: Chattanooga Continuum Device (DEVICE).
Who is sponsoring clinical trial NCT06830876?
This trial is sponsored by Sara Peterson-Snyder, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06830876 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amputation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06830876's enrollment target sits among peer trials
20 33rd of 65 higher than 25 of 65 other Amputation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amputation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation
RECRUITING · NA
-
Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment
RECRUITING · NA
-
Hand Transplantation
RECRUITING · NA
-
Target Muscle Re-innervation and Regenerative Peripheral Nerve Interfaces Alone and in Combination for the Treatment of Residual and Phantom Limb Pain in Cancer Patients Who Have Received an Amputation
RECRUITING · NA
-
Can an Array of Micro-electrodes Implanted in a Human Nerve Record Neural Signals and Provide Feedback?
RECRUITING · NA
-
Intuitive Control of a Hybrid Prosthetic Leg During Ambulation
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00573339 · 20 participants
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
- NCT00692939 · 20 participants · Phase 1
Autologous Stem Cell Transplantation for Crohn's Disease
- NCT00967785 · 20 participants · Phase 1
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- NCT01406691 · 20 participants · Phase 4
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI