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NCT06828666 · ClinicalTrials.gov registry record · Phase 1
A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee
A Phase 1 study of Osteoarthritis of Knee, sponsored by Britecyte.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 42
- Enrollment target
- 7
- Study locations
NCT06828666 is a Phase 1 study of Osteoarthritis of Knee that is actively recruiting participants, run by Britecyte. The registered enrollment target is 42 participants, below the 227-participant average among 3 other Osteoarthritis of Knee trials with a reported enrollment target (81% lower). The trial reports 7 study locations across 3 states.
The verdict
NCT06828666, a Phase 1 study of Osteoarthritis of Knee, is actively recruiting participants, sponsored by Britecyte.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 42 participants
- Enrollment target
- 7
- Study locations
Study Summary
The purpose of this study is to evaluate the safety profile of BRC-OA for pain treatment in patients with mild to severe OA of the knee, focusing particularly on two distinct doses. Alongside safety assessments, the study also aims to investigate the initial efficacy of BRC-OA in treating pain among these patients. The study product is a cryopreserved devitalized adipose tissue allograft (BRC-OA). BRC-OA is composed of a devitalized human adipose particulate that retains the inherent properties of adipose such as tissue architecture, extracellular matrix, and signaling molecules.
Conditions Studied
Interventions
- BIOLOGICAL Cryopreserved Devitalized Adipose Tissue Allograft
- OTHER Normal Saline (Placebo)
Study Locations (7)
Maryland
- LifeBridge Health - Baltimore
- The Osteoporosis & Clinical Trials Center - Hagerstown
- MD Medical Research - Oxon Hill
- Elevate Clinical Research - Rockville
Pennsylvania
- University Orthopedics Center - Altoona
- University Orthopedics Center - State College
New York
- Northwell Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2025-05-05 |
| Est. Completion | 2026-04 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06828666
The ClinicalTrials.gov registry entry for NCT06828666 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 227-participant average among 3 other Osteoarthritis of Knee trials with a reported enrollment target (81% lower). The listed sponsor is Britecyte, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Osteoarthritis of Knee appearing as the primary indexed condition, and to 2 interventions - of which Cryopreserved Devitalized Adipose Tissue Allograft is the first listed.
NCT06828666 reports 7 study locations spanning 3 distinct geographic areas - top geographies include Maryland, Pennsylvania, New York.
Frequently Asked Questions
What is clinical trial NCT06828666 about?
NCT06828666 is a clinical study titled "A Phase 1/2a to Evaluate the Safety and Efficacy of Adipose Tissue Allograft (BRC-OA) in Patients With Osteoarthritis of the Knee". The purpose of this study is to evaluate the safety profile of BRC-OA for pain treatment in patients with mild to severe OA of the knee, focusing particularly on two distinct doses. Alongside safety assessments, the study also aims to investigate the initial efficacy of BRC-OA in treating pain among...
What is the current status of trial NCT06828666?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 42 participants. The study started on 2025-05-05. Estimated completion is 2026-04.
What conditions does trial NCT06828666 study?
This clinical trial studies the following conditions: Osteoarthritis of Knee.
What interventions are being tested in trial NCT06828666?
The interventions under investigation include: Cryopreserved Devitalized Adipose Tissue Allograft (BIOLOGICAL), Normal Saline (Placebo) (OTHER).
Who is sponsoring clinical trial NCT06828666?
This trial is sponsored by Britecyte, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06828666 being conducted?
This trial has 7 study locations across Maryland, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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