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NCT06805877 · ClinicalTrials.gov registry record · NA
Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing
A NA study of HIV, sponsored by Harvard Pilgrim Health Care.
- Active
- Registry status
- NA
- Development phase
- 16
- Enrollment target
- 16
- Study locations
NCT06805877: Active NA study of HIV, sponsored by Harvard Pilgrim Health Care.
NCT06805877 is a NA study of HIV that is active but no longer recruiting, run by Harvard Pilgrim Health Care. The registered enrollment target is 16 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (96% lower). The trial reports 16 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06805877, a NA study of HIV, is active but no longer recruiting, sponsored by Harvard Pilgrim Health Care.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
- 16
- Study locations
Study Summary
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the U.S. initiative to end the HIV epidemic, but healthcare providers lack tools to support PrEP discussions and prescribing for patients likely to benefit. This research will evaluate whether integrating automated tools into electronic health records to help providers efficiently and equitably identify potential candidates for PrEP, discuss PrEP, and prescribe PrEP can improve PrEP initiation and persistence in safety-net community health centers. It will achieve this by conducting a stepped-wedge trial of a decision support tool with an embedded HIV prediction model to identify patients likely to benefit from PrEP. The intervention will be delivered to healthcare providers in 16 community health centers within the national OCHIN network.
Primary Outcome
Proportion of patients above the prediction model risk threshold without a recently active PrEP prescription (within the prior 6 months) or prior HIV diagnosis who are prescribed PrEP during the study period.
Conditions Studied
Interventions
- OTHER Predictive Analytics and Clinical Decision Support
Study Locations (16)
California
- Bay Area Community Health Liberty Clinic - Fremont
- Lifelong East Oakland Health Center - Oakland
- TrueCare Oceanside Family Medicine - Oceanside
- DAP Legacy - Palm Springs
- One Community Health Midtown Campus - Sacramento
Massachusetts
- Lynn Community Health Center 269 Union - Lynn
- Mattapan Community Health Center Blue Hill - Mattapan
Ohio
- Neighborhood Family Practice Ridge Community Health Center - Cleveland
- Signature Health Painesville - Painesville
Connecticut
- Southwest Community Health Center 968 Fairfield Avenue - Bridgeport
Georgia
- Mercy Care Decatur Street - Atlanta
Iowa
- Siouxland Community Health Center Sioux City - Sioux City
Oklahoma
- Variety Care Sequoyah - Oklahoma City
Oregon
- Prism Belmont - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-04-21 |
| Est. Completion | 2030-07 |
| Phase | NA |
What the registry record for NCT06805877 still lists
NCT06805877 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 440-participant average among 303 other HIV trials with a reported enrollment target (96% lower).
The record links to 1 condition, with HIV appearing as the primary indexed condition, and to 1 intervention - of which Predictive Analytics and Clinical Decision Support is the first listed.
NCT06805877 lists 16 locations in 10 states (California, Massachusetts, Ohio).
Frequently Asked Questions
What is clinical trial NCT06805877 about?
NCT06805877 is a clinical study titled "Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing". Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the U.S. initiative to end the HIV epidemic, but healthcare providers lack tools to support PrEP discussions and prescribing for patients likely to benefit. This research will evaluate whether integrating automated tools into electr...
What is the current status of trial NCT06805877?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 16 participants. The study started on 2025-04-21. Estimated completion is 2030-07.
What conditions does trial NCT06805877 study?
This clinical trial studies the following conditions: HIV.
What interventions are being tested in trial NCT06805877?
The interventions under investigation include: Predictive Analytics and Clinical Decision Support (OTHER).
Who is sponsoring clinical trial NCT06805877?
This trial is sponsored by Harvard Pilgrim Health Care, which has 28 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06805877 being conducted?
This trial has 16 study locations across California, Connecticut, Georgia, Iowa, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT06805877's enrollment target sits among peer trials
16 288th of 303 higher than 15 of 303 other HIV trials
participants (enrollment target), bucketed by value
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