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NCT06801002 · ClinicalTrials.gov registry record · Phase 1
Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies
A Phase 1 study of Solid Tumor, sponsored by Jabez Bioscience.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 25
- Enrollment target
- 2
- Study locations
NCT06801002: Recruiting Phase 1 study of Solid Tumor, sponsored by Jabez Bioscience.
NCT06801002 is a Phase 1 study of Solid Tumor that is actively recruiting participants, run by Jabez Bioscience. The registered enrollment target is 25 participants, below the 222-participant average among 196 other Solid Tumor trials with a reported enrollment target (89% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06801002, a Phase 1 study of Solid Tumor, is actively recruiting participants, sponsored by Jabez Bioscience.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 25 participants
- Enrollment target
- 2
- Study locations
Study Summary
This will be a phase 1, open-label, dose-escalation and expansion, FIH trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of JBZ-001, a DHODH inhibitor, in patients with refractory solid and hematological malignancies. The study design includes two independent parts: dose escalation in solid tumors and NHL (Part 1), and up to four indication expansions in selected solid tumor types and NHL (Part 2). The dose escalation will enroll patients with solid tumors and NHL following a standard "3+3" design enrolling a minimum of 3 and up to 6 patients per dose level.
Primary Outcome
Evaluation of adverse events
Conditions Studied
Interventions
- DRUG JBZ-001
Study Locations (2)
Ohio
- The Ohio State University - Columbus
Utah
- START Mountain Region - West Valley City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2025-03-17 |
| Est. Completion | 2028-02-15 |
| Phase | Phase 1 |
What NCT06801002 shows while recruiting
NCT06801002 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 222-participant average among 196 other Solid Tumor trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which JBZ-001 is the first listed.
NCT06801002 reports a single indexed study location in Ohio, Utah.
Frequently Asked Questions
What is clinical trial NCT06801002 about?
NCT06801002 is a clinical study titled "Trial to Evaluate the Safety & Tolerability of JBZ-001 in Pts With Advanced Solid and Hematological Malignancies". This will be a phase 1, open-label, dose-escalation and expansion, FIH trial to evaluate the safety, tolerability, PK, PD, and preliminary efficacy of JBZ-001, a DHODH inhibitor, in patients with refractory solid and hematological malignancies. The study design includes two independent parts: dose e...
What is the current status of trial NCT06801002?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 25 participants. The study started on 2025-03-17. Estimated completion is 2028-02-15.
What conditions does trial NCT06801002 study?
This clinical trial studies the following conditions: Solid Tumor.
What interventions are being tested in trial NCT06801002?
The interventions under investigation include: JBZ-001 (DRUG).
Who is sponsoring clinical trial NCT06801002?
This trial is sponsored by Jabez Bioscience, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06801002 being conducted?
This trial has 2 study locations across Ohio, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Solid Tumor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06801002's enrollment target sits among peer trials
25 167th of 196 higher than 28 of 196 other Solid Tumor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Solid Tumor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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