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NCT06788938 · ClinicalTrials.gov registry record · Phase 2

Tarlatamab in Advanced Delta-like 3 (DLL3)-Expressing Tumors Including Neuroendocrine Neoplasms

A Phase 2 study of Advanced Tumors and DLL3-expressing Tumors, sponsored by Jonsson Comprehensive Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
29
Enrollment target
5
Study locations

NCT06788938: Recruiting Phase 2 study of Advanced Tumors and DLL3-expressing Tumors, sponsored by Jonsson Comprehensive Cancer Center.

NCT06788938 is a Phase 2 study of Advanced Tumors and DLL3-expressing Tumors that is actively recruiting participants, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 29 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower). The trial reports 5 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06788938, a Phase 2 study of Advanced Tumors and DLL3-expressing Tumors, is actively recruiting participants, sponsored by Jonsson Comprehensive Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
29 participants
Enrollment target
5
Study locations

Study Summary

This study is being done to learn more about the drug tarlatamab in people with your condition. The purpose of this study is to see the efficacy (how well something works) of study treatment (tarlatamab) and whether it causes any side effects. Tarlatamab is being developed as an anti-cancer drug for tumors and is FDA-approved for extensive-stage small cell lung cancer. Tarlatamab is investigational for the purpose of this study.

Interventions

  • DRUG Tarlatamab treatment

Study Locations (5)

California

  • UC Davis Comprehensive Cancer Center - Davis
  • UCI Health Chao Family Comprehensive Cancer Center - Irvine
  • University of California at Los Angeles - Los Angeles
  • UC San Diego Moores Cancer Center - San Diego
  • University of California at San Francisco - San Francisco

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2025-03-21
Est. Completion 2029-04-24
Phase Phase 2
Jonsson Comprehensive Cancer Center

321 total trials

What NCT06788938 shows while recruiting

NCT06788938 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (78% lower).

The record links to 2 conditions, with Advanced Tumors appearing as the primary indexed condition, and to 1 intervention - of which Tarlatamab treatment is the first listed.

NCT06788938 lists 5 locations in 1 state (California).

Frequently Asked Questions

What is clinical trial NCT06788938 about?

NCT06788938 is a clinical study titled "Tarlatamab in Advanced Delta-like 3 (DLL3)-Expressing Tumors Including Neuroendocrine Neoplasms". This study is being done to learn more about the drug tarlatamab in people with your condition. The purpose of this study is to see the efficacy (how well something works) of study treatment (tarlatamab) and whether it causes any side effects. Tarlatamab is being developed as an anti-cancer drug for...

What is the current status of trial NCT06788938?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2025-03-21. Estimated completion is 2029-04-24.

What conditions does trial NCT06788938 study?

This clinical trial studies the following conditions: Advanced Tumors, DLL3-expressing Tumors.

What interventions are being tested in trial NCT06788938?

The interventions under investigation include: Tarlatamab treatment (DRUG).

Who is sponsoring clinical trial NCT06788938?

This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06788938 being conducted?

This trial has 5 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Advanced Tumors

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06788938's enrollment target sits among peer trials

29 1669th of 2000 higher than 324 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06788938, the US trial registry maintained by the National Library of Medicine. NCT06788938 (small enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.