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NCT06777784 · ClinicalTrials.gov registry record · NA
Modern Nicotine Oral Product Abuse Liability
A NA study of Smoking and Tobacco Use, sponsored by RAI Services Company.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT06777784: Completed NA study of Smoking and Tobacco Use, sponsored by RAI Services Company.
NCT06777784 is a NA study of Smoking and Tobacco Use that has completed, run by RAI Services Company. The registered enrollment target is 40 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (91% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06777784, a NA study of Smoking and Tobacco Use, has completed, sponsored by RAI Services Company.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a two-site, open-label, randomized, 8-way cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics \[PD\]) and plasma nicotine uptake (pharmacokinetics \[PK\]) during and following ad libitum use of the study investigational products (IPs) by generally healthy smokers.
Primary Outcome
area under the effect curve (AUEC) for PL (VAS score-versus-time)
Conditions Studied
Interventions
- OTHER Product A
- OTHER Product B
- OTHER Product C
- OTHER Product D
- OTHER Product E
Study Locations (2)
Kentucky
- AMR Lexington - Lexington
Tennessee
- AMR Knoxville - Knoxville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-02-03 |
| Est. Completion | 2025-03-05 |
| Phase | NA |
What the finished NCT06777784 record still lists
NCT06777784 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Smoking appearing as the primary indexed condition, and to 5 interventions - of which Product A is the first listed.
NCT06777784 reports a single indexed study location in Kentucky, Tennessee.
Frequently Asked Questions
What is clinical trial NCT06777784 about?
NCT06777784 is a clinical study titled "Modern Nicotine Oral Product Abuse Liability". This is a two-site, open-label, randomized, 8-way cross-over study designed to evaluate elements of abuse liability (AL) including subjective effects and physiological measures (pharmacodynamics \[PD\]) and plasma nicotine uptake (pharmacokinetics \[PK\]) during and following ad libitum use of the s...
What is the current status of trial NCT06777784?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2025-02-03. Estimated completion is 2025-03-05.
What conditions does trial NCT06777784 study?
This clinical trial studies the following conditions: Smoking, Tobacco Use.
What interventions are being tested in trial NCT06777784?
The interventions under investigation include: Product A (OTHER), Product B (OTHER), Product C (OTHER), Product D (OTHER), Product E (OTHER).
Who is sponsoring clinical trial NCT06777784?
This trial is sponsored by RAI Services Company, which has 42 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06777784 being conducted?
This trial has 2 study locations across Kentucky, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06777784's enrollment target sits among peer trials
40 102nd of 123 higher than 18 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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