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NCT06769464 · ClinicalTrials.gov registry record · NA

Electrophysiological Representations of Odor in the Human Brain Study 1

A NA study of Odor Intensity Ratings, sponsored by Northwestern University.

Recruiting
Registry status
NA
Development phase
28
Enrollment target
1
Study location

NCT06769464: Recruiting NA study of Odor Intensity Ratings, sponsored by Northwestern University.

NCT06769464 is a NA study of Odor Intensity Ratings that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 28 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06769464, a NA study of Odor Intensity Ratings, is actively recruiting participants, sponsored by Northwestern University.

RECRUITING
Registry status
NA
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

Investigating representations of odor intensity in human piriform cortex. To identify a neural representation of perceived odor intensity, it is necessary to dissociate stimulus concentration from perceived intensity. Experiments for this aim will measure human perceptual responses while manipulating intensity independently from concentration using two complementary approaches. In Experiment 1A, we will match perceived intensities across odors of different concentrations, allowing us to identify a neural representation of intensity that is independent of stimulus identity and concentration. In Experiment 1B, we will create conditions of different perceived intensity over constant odor stimuli using adaptation. Approaching the same question from different angles will strengthen the robustness of our findings. Preliminary data suggest that temporal features of the piriform neural response may represent odor intensity.

Primary Outcome

Odors of different concentrations will be presented, and we will obtain behavioral ratings on a GLMS scale of intensity presented on a laptop computer, converted into Matlab for analysis

Conditions Studied

Interventions

  • BEHAVIORAL odor

Study Locations (1)

Illinois

  • Northwestern University - Chicago

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2024-04-01
Est. Completion 2028-08-01
Phase NA
Northwestern University

1,209 total trials

What NCT06769464 shows while recruiting

NCT06769464 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Odor Intensity Ratings appearing as the primary indexed condition, and to 1 intervention - of which odor is the first listed.

NCT06769464 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT06769464 about?

NCT06769464 is a clinical study titled "Electrophysiological Representations of Odor in the Human Brain Study 1". Investigating representations of odor intensity in human piriform cortex. To identify a neural representation of perceived odor intensity, it is necessary to dissociate stimulus concentration from perceived intensity. Experiments for this aim will measure human perceptual responses while manipulatin...

What is the current status of trial NCT06769464?

This trial is currently recruiting. It is a NA study. The enrollment target is 28 participants. The study started on 2024-04-01. Estimated completion is 2028-08-01.

What conditions does trial NCT06769464 study?

This clinical trial studies the following conditions: Odor Intensity Ratings.

What interventions are being tested in trial NCT06769464?

The interventions under investigation include: odor (BEHAVIORAL).

Who is sponsoring clinical trial NCT06769464?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06769464 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT06769464's enrollment target sits among peer trials

28 1704th of 2000 higher than 293 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06769464, the US trial registry maintained by the National Library of Medicine. NCT06769464 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.