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RECRUITING Phase 3

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

NCT06767514 · View on ClinicalTrials.gov ↗

Study Summary

Clinical study of ivonescimab for first-line treatment of metastatic NSCLC patients with high PD-L1. Evaluating overall survival and progression free survival.

Conditions Studied

Interventions

  • BIOLOGICAL Ivonescimab Injection
  • BIOLOGICAL Pembrolizumab Injection

Study Locations (20)

California

  • Clinical Study Site — Cerritos
  • Clinical Study Site — Glendale
  • Clinical Study Site — Irvine
  • Clinical Study Site — Los Angeles
  • Clinical Study Site — Mountain View
  • Clinical Study Site — Murrieta
  • Clinical Study Site — Newport Beach
  • Clinical Study Site — Roseville
  • Clinical Study Site — Sacramento
  • Clinical Study Site — San Diego
  • Clinical Study Site — San Francisco
  • Clinical Study Site — Santa Ana
  • Clinical Study Site — Whittier

Colorado

  • Clinical Study Site — Aurora
  • Clinical Study Site — Grand Junction
  • Clinical Study Site — Greeley
  • Clinical Study Site — Lone Tree

Arizona

  • Clinical Study Site — Chandler
  • Clinical Study Site — Phoenix

Arkansas

  • Clinical Study Site — Hot Springs

Trial Details

FieldValue
Enrollment Target 780 participants
Start Date 2025-02-27
Est. Completion 2029-06
Phase Phase 3

Sponsor

Summit Therapeutics

59 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06767514

The ClinicalTrials.gov registry entry for NCT06767514 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 780 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Summit Therapeutics, which has 59 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 2 interventions — of which Ivonescimab Injection is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06767514 reports 20 study locations spanning 4 distinct geographic areas — top geographies include California, Colorado, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06767514 about?

NCT06767514 is a clinical study titled "Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1". Clinical study of ivonescimab for first-line treatment of metastatic NSCLC patients with high PD-L1. Evaluating overall survival and progression free survival.

What is the current status of trial NCT06767514?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 780 participants. The study started on 2025-02-27. Estimated completion is 2029-06.

What conditions does trial NCT06767514 study?

This clinical trial studies the following conditions: Non-Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06767514?

The interventions under investigation include: Ivonescimab Injection (BIOLOGICAL), Pembrolizumab Injection (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06767514?

This trial is sponsored by Summit Therapeutics, which has 59 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06767514 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial