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A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer
NCT06764485 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to compare the efficacy and safety of BMS-986365 versus the investigator's choice of therapy in participants with Metastatic Castration-resistant Prostate Cancer.
Conditions Studied
Interventions
- DRUG Docetaxel
- DRUG Enzalutamide
- DRUG Abiraterone
- DRUG BMS-986365
- DRUG Predinsone/Prednisolone
Study Locations (20)
California
- Los Angeles Cancer Network (LACN) — Anaheim
- Moores Cancer Center — La Jolla
- Cancer and Blood Specialty Clinic — Los Alamitos
- Local Institution - 0364 — Los Angeles
- Pacific Hematology Oncology Associates — San Francisco
- San Francisco VA Health Care System — San Francisco
Colorado
- Rocky Mountain Regional VA Medical Center — Aurora
- Rocky Mountain Cancer Centers, LLP — Denver
- Colorado Clinical Research — Lakewood
Maryland
- Chesapeake Urology — Baltimore
- Johns Hopkins Hospital — Baltimore
- James M Stockman Cancer Institute — Frederick
Kansas
- The University of Kansas Cancer Center - Westwood — Westwood
- Wichita Urology Group — Wichita
Alabama
- Central Alabama Research — Birmingham
Arizona
- Banner MD Anderson Cancer Center — Gilbert
District of Columbia
- Sibley Memorial Hospital — Washington D.C.
Florida
- Lakeland Regional Cancer Center — Lakeland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 960 participants |
| Start Date | 2025-03-13 |
| Est. Completion | 2029-01-19 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06764485
The ClinicalTrials.gov registry entry for NCT06764485 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 960 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Celgene, which has 73 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Metastatic Castration-resistant Prostate Cancer appearing as the primary indexed condition, and to 5 interventions — of which Docetaxel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06764485 reports 20 study locations spanning 10 distinct geographic areas — top geographies include California, Colorado, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06764485 about?
NCT06764485 is a clinical study titled "A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer". The purpose of this study is to compare the efficacy and safety of BMS-986365 versus the investigator's choice of therapy in participants with Metastatic Castration-resistant Prostate Cancer.
What is the current status of trial NCT06764485?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 960 participants. The study started on 2025-03-13. Estimated completion is 2029-01-19.
What conditions does trial NCT06764485 study?
This clinical trial studies the following conditions: Metastatic Castration-resistant Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06764485?
The interventions under investigation include: Docetaxel (DRUG), Enzalutamide (DRUG), Abiraterone (DRUG), BMS-986365 (DRUG), Predinsone/Prednisolone (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06764485?
This trial is sponsored by Celgene, which has 73 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06764485 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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