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A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
NCT07213674 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to compare overall survival (OS) in participants receiving xaluritamig plus abiraterone against investigator's choice (docetaxel, cabazitaxel, or abiraterone).
Conditions Studied
Interventions
- DRUG Docetaxel
- DRUG Xaluritamig
- DRUG Cabazitaxel
- DRUG Abiraterone acetate
Study Locations (20)
Other
- Ordensklinikum Linz Elisabethinen — Linz
- Universitaetsklinikum Sankt Poelten — Sankt Pölten
- Krankenhaus der Barmherzigen Brueder Wien — Vienna
- Universitaetsklinikum Allgemeines Krankenhaus Wien — Vienna
California
- City of Hope National Medical Center — Duarte
- City of Hope Orange County Lennar Foundation Cancer Center — Duarte
- Providence Saint Jude Medical Center — Fullerton
Queensland
- Icon Cancer Care Wesley — Herston
- Tasman Oncology Research — Southport
Victoria
- Monash Medical Centre — Clayton
- Austin Health, Austin Hospital — East Melbourne
Colorado
- Rocky Mountain Cancer Centers — Denver
Illinois
- University of Illinois Chicago — Chicago
Kentucky
- Norton Cancer Institute — Louisville
Ohio
- Oncology Hematology Care Incorporated — Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 750 participants |
| Start Date | 2025-11-28 |
| Est. Completion | 2032-08-30 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07213674
The ClinicalTrials.gov registry entry for NCT07213674 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 750 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 266 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Metastatic Castration-resistant Prostate Cancer appearing as the primary indexed condition, and to 4 interventions — of which Docetaxel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07213674 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Other, California, Queensland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07213674 about?
NCT07213674 is a clinical study titled "A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer". The primary objective of this study is to compare overall survival (OS) in participants receiving xaluritamig plus abiraterone against investigator's choice (docetaxel, cabazitaxel, or abiraterone).
What is the current status of trial NCT07213674?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 750 participants. The study started on 2025-11-28. Estimated completion is 2032-08-30.
What conditions does trial NCT07213674 study?
This clinical trial studies the following conditions: Metastatic Castration-resistant Prostate Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07213674?
The interventions under investigation include: Docetaxel (DRUG), Xaluritamig (DRUG), Cabazitaxel (DRUG), Abiraterone acetate (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07213674?
This trial is sponsored by Amgen, which has 266 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07213674 being conducted?
This trial has 20 study locations across California, Colorado, Illinois, Kentucky, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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