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NCT06741228 · ClinicalTrials.gov registry record · Phase 3
A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)
A Phase 3 study of Generalized Anxiety Disorder, sponsored by Definium Therapeutics US.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 200
- Enrollment target
- 20
- Study locations
NCT06741228: Recruiting Phase 3 study of Generalized Anxiety Disorder, sponsored by Definium Therapeutics US.
NCT06741228 is a Phase 3 study of Generalized Anxiety Disorder that is actively recruiting participants, run by Definium Therapeutics US. The registered enrollment target is 200 participants, roughly in line with the 211-participant average among 48 other Generalized Anxiety Disorder trials with a reported enrollment target. The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06741228, a Phase 3 study of Generalized Anxiety Disorder, is actively recruiting participants, sponsored by Definium Therapeutics US.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 200 participants
- Enrollment target
- 20
- Study locations
Study Summary
A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Generalized Anxiety Disorder - Voyage
Primary Outcome
The HAM-A consists of the following 14 items that encompass both psychological and somatic symptoms of anxiety. Each item is scored on a scale of 0 (not present) to 4 (severe), with a total score range of 0-56, where \<17 indicates mild severity, 18-24 mild to moderate severity and 25-30 moderate to severe.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG MM120 (LSD D-Tartrate)
Study Locations (20)
California
- Kadima Neuropsychiatry Institute - La Jolla
- UCSF Department of Neurology - San Francisco
- Psychedelic Science Institute - Santa Monica
Florida
- Clinical Neuroscience Solutions Inc. - Jacksonville
- Accel Research Sites - Lakeland CRU - Lakeland
- Segal Trials - Lauderhill
Georgia
- Atlanta Center for Medical Research - Atlanta
- iResearch Atlanta - Decatur
- CenExel iResearch, LLC - Savannah
New York
- Spectrum Neuroscience and Treatment Institute - New York
- Adams Clinical Harlem - New York
- New York State Psychiatric Institute (NYSPI) - New York
Arizona
- Lighthouse Psychiatry - Gilbert
- Scottsdale Research Institute - Scottsdale
Massachusetts
- Adams Clinical Boston - Boston
- Adams Clinical Watertown - Watertown
Colorado
- Mountain View - Denver
Illinois
- Uptown Research Institute - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-12-11 |
| Est. Completion | 2026-11 |
| Phase | Phase 3 |
What NCT06741228 shows while recruiting
NCT06741228 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 211-participant average among 48 other Generalized Anxiety Disorder trials with a reported enrollment target.
The record links to 1 condition, with Generalized Anxiety Disorder appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06741228 names 20 study sites across 10 states, led by California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT06741228 about?
NCT06741228 is a clinical study titled "A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Voyage)". A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Generalized Anxiety Disorder - Voyage
What is the current status of trial NCT06741228?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 200 participants. The study started on 2024-12-11. Estimated completion is 2026-11.
What conditions does trial NCT06741228 study?
This clinical trial studies the following conditions: Generalized Anxiety Disorder.
What interventions are being tested in trial NCT06741228?
The interventions under investigation include: Placebo (OTHER), MM120 (LSD D-Tartrate) (DRUG).
Who is sponsoring clinical trial NCT06741228?
This trial is sponsored by Definium Therapeutics US, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06741228 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06741228's enrollment target sits among peer trials
200 18th of 48 higher than 31 of 48 other Generalized Anxiety Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Generalized Anxiety Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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