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NCT06735014 · ClinicalTrials.gov registry record
Multicenter ALS Imaging Study
A clinical trial of Amyotrophic Lateral Sclerosis and ALS, sponsored by University of Minnesota.
- Recruiting
- Registry status
- 90
- Enrollment target
- 3
- Study locations
NCT06735014: Recruiting study of Amyotrophic Lateral Sclerosis and ALS, sponsored by University of Minnesota.
NCT06735014 is a study of Amyotrophic Lateral Sclerosis and ALS that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 90 participants, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (90% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06735014, a study of Amyotrophic Lateral Sclerosis and ALS, is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- 90 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a multi-site study of ALS participants and healthy controls who will undergo brain and cervical spine MRIs and NfL blood testing at up-to 4 time points over the course of a year. The primary goal is to identify objective biomarkers of disease progression that are biologically relevant, linearly progressive, and sensitive to change.
Primary Outcome
This measure comes from the biophysical model used in brain imaging and is collected using MRI. It refers to the volume of the intra-axonal compartment per unit volume of the tissue. As this is a fraction it does not have a unit.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Magnetic Resonance Imaging
- DIAGNOSTIC_TEST Plasma neurofilament light chain (NfL) quantification
Study Locations (3)
Florida
- University of Florida - Gainesville
Illinois
- Northwestern University - Evanston
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2024-09-15 |
| Est. Completion | 2028-08-31 |
What NCT06735014 shows while recruiting
NCT06735014 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 897-participant average among 102 other Amyotrophic Lateral Sclerosis trials with a reported enrollment target (90% lower).
The record links to 2 conditions, with Amyotrophic Lateral Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Magnetic Resonance Imaging is the first listed.
NCT06735014 reports a single indexed study location in Florida, Illinois, Minnesota.
Frequently Asked Questions
What is clinical trial NCT06735014 about?
NCT06735014 is a clinical study titled "Multicenter ALS Imaging Study". This is a multi-site study of ALS participants and healthy controls who will undergo brain and cervical spine MRIs and NfL blood testing at up-to 4 time points over the course of a year. The primary goal is to identify objective biomarkers of disease progression that are biologically relevant, linea...
What is the current status of trial NCT06735014?
This trial is currently recruiting. The enrollment target is 90 participants. The study started on 2024-09-15. Estimated completion is 2028-08-31.
What conditions does trial NCT06735014 study?
This clinical trial studies the following conditions: Amyotrophic Lateral Sclerosis, ALS.
What interventions are being tested in trial NCT06735014?
The interventions under investigation include: Magnetic Resonance Imaging (DIAGNOSTIC_TEST), Plasma neurofilament light chain (NfL) quantification (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06735014?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06735014 being conducted?
This trial has 3 study locations across Florida, Illinois, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Amyotrophic Lateral Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06735014's enrollment target sits among peer trials
90 42nd of 102 higher than 60 of 102 other Amyotrophic Lateral Sclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Amyotrophic Lateral Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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