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NCT06734208 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Pharmacokinetics of Divarasib in Healthy Participants and Participants With Impaired Hepatic Function
A Phase 1 study, sponsored by Genentech.
- Completed
- Registry status
- Phase 1
- Development phase
- 31
- Enrollment target
NCT06734208: Completed Phase 1 study, sponsored by Genentech.
NCT06734208 is a Phase 1 study that has completed, run by Genentech. The registered enrollment target is 31 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06734208, a Phase 1 study, has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 31 participants
- Enrollment target
Study Summary
This is a phase 1, open-label, single-dose, parallel-cohort study to determine the pharmacokinetics (PK) of divarasib in healthy participants and participants with varying degrees of hepatic impairment, as defined by Child-Pugh classification.
Interventions
- DRUG Divarasib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2025-01-31 |
| Est. Completion | 2025-11-27 |
| Phase | Phase 1 |
What the finished NCT06734208 record still lists
NCT06734208 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 31 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (48% lower).
The record links to 0 conditions, and to 1 intervention - of which Divarasib is the first listed.
NCT06734208 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06734208 about?
NCT06734208 is a clinical study titled "A Study to Evaluate the Pharmacokinetics of Divarasib in Healthy Participants and Participants With Impaired Hepatic Function". This is a phase 1, open-label, single-dose, parallel-cohort study to determine the pharmacokinetics (PK) of divarasib in healthy participants and participants with varying degrees of hepatic impairment, as defined by Child-Pugh classification.
What is the current status of trial NCT06734208?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 31 participants. The study started on 2025-01-31. Estimated completion is 2025-11-27.
What interventions are being tested in trial NCT06734208?
The interventions under investigation include: Divarasib (DRUG).
Who is sponsoring clinical trial NCT06734208?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06734208's enrollment target sits among peer trials
31 1322nd of 2000 higher than 669 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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