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NCT06733376 · ClinicalTrials.gov registry record · NA

Evaluating Evidenced Based Options for PTSD Treatment

A NA study of PTSD - Post Traumatic Stress Disorder, sponsored by Rush University Medical Center.

Recruiting
Registry status
NA
Development phase
400
Enrollment target
1
Study location

NCT06733376: Recruiting NA study of PTSD - Post Traumatic Stress Disorder, sponsored by Rush University Medical Center.

NCT06733376 is a NA study of PTSD - Post Traumatic Stress Disorder that is actively recruiting participants, run by Rush University Medical Center. The registered enrollment target is 400 participants, above the 251-participant average among 14 other PTSD - Post Traumatic Stress Disorder trials with a reported enrollment target (59% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06733376, a NA study of PTSD - Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Rush University Medical Center.

RECRUITING
Registry status
NA
Development phase
400 participants
Enrollment target
1
Study location

Study Summary

This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment. The goal is to improve personalized care by: Identifying factors that might predict how someone will respond to a second treatment. Creating a simple tool to spot people who might not respond to treatment early, so they can start a different option sooner. The findings will help improve PTSD care by offering better follow-up treatments and matching patients with the approach that works best for them.

Primary Outcome

A self-report measure of PTSD symptom severity

Interventions

  • BEHAVIORAL Cognitive Processing Therapy
  • BEHAVIORAL Prolonged Exposure
  • BEHAVIORAL Skills Training for Affective and Interpersonal Regulation

Study Locations (1)

Illinois

  • Rush University Medical Center - Chicago

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2025-10-06
Est. Completion 2030-06-01
Phase NA
Rush University Medical Center

320 total trials

What NCT06733376 shows while recruiting

NCT06733376 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, above the 251-participant average among 14 other PTSD - Post Traumatic Stress Disorder trials with a reported enrollment target (59% higher).

The record links to 1 condition, with PTSD - Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 3 interventions - of which Cognitive Processing Therapy is the first listed.

NCT06733376 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT06733376 about?

NCT06733376 is a clinical study titled "Evaluating Evidenced Based Options for PTSD Treatment". This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment. The goal is to improve personalized care by: Identifying factors that might predict how someone will respond to ...

What is the current status of trial NCT06733376?

This trial is currently recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2025-10-06. Estimated completion is 2030-06-01.

What conditions does trial NCT06733376 study?

This clinical trial studies the following conditions: PTSD - Post Traumatic Stress Disorder.

What interventions are being tested in trial NCT06733376?

The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL), Prolonged Exposure (BEHAVIORAL), Skills Training for Affective and Interpersonal Regulation (BEHAVIORAL).

Who is sponsoring clinical trial NCT06733376?

This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06733376 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for PTSD - Post Traumatic Stress Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06733376's enrollment target sits among peer trials

400 3rd of 14 higher than 12 of 14 other PTSD - Post Traumatic Stress Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other PTSD - Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06733376, the US trial registry maintained by the National Library of Medicine. NCT06733376 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.