Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07107269 · ClinicalTrials.gov registry record · NA
Diet and Microbiome Interactions: Application in Posttraumatic Stress Disorder in Adults Consuming Vegetable Drinks
A NA study of PTSD - Post Traumatic Stress Disorder, sponsored by Colorado State University.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07107269: Recruiting NA study of PTSD - Post Traumatic Stress Disorder, sponsored by Colorado State University.
NCT07107269 is a NA study of PTSD - Post Traumatic Stress Disorder that is actively recruiting participants, run by Colorado State University. The registered enrollment target is 40 participants, below the 277-participant average among 14 other PTSD - Post Traumatic Stress Disorder trials with a reported enrollment target (86% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07107269, a NA study of PTSD - Post Traumatic Stress Disorder, is actively recruiting participants, sponsored by Colorado State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The gut microbiome has been shown to impact various facets of human health, including mental health. Studies have shown that populations with more agrarian lifestyles tend to have fewer chronic diseases and mental health issues than industrialized populations. A possible factor in these differences is the loss of co-evolved gut microbial taxa that has occurred with Westernization. This hypothesis, termed "Old Friends Hypothesis" suggests that the loss of certain gut microbes leads to immune dysregulation and increased chronic inflammation that contributes to development of cancers, cardiometabolic diseases and even neuroinflammation that can lead to negative behavioral and mental health outcomes. Other studies have shown that increasing the intake of plant foods may help increase diversity of the microbes in the gut and that this increased diversity could lead to better health outcomes in humans. The investigators propose to evaluate daily consumption of a drink consisting of a high diversity of plants (30 plant species) for four weeks on the diversity of the gut microbiome, biological signatures of inflammation, quality of life, sleep quality, and PTSD symptoms among persons with a diagnosis of PTSD. The investigators hypothesize that four weeks of daily consumption of this high plant diversity beverage (30 plant species) will increase gut microbiome ɑ-diversity, reduce markers of systemic inflammation, and improve PTSD symptom severity relative to daily consumption of a beverage containing only three plant species.
Primary Outcome
PTSD Checklist for DSM-5 or the PCL-5 questionnaire. The PCL-5 is a 20-item self-report measure that assesses the 20 DSM-5 symptoms of PTSD. The PCL-5 has a variety of purposes, including: Monitoring symptom change during and after treatment Screening individuals for PTSD Making a provisional PTSD diagnosis A higher score on the PCL-5 indicates a greater level of distress and impairment associated with PTSD symptoms. The total score ranges from 0 to 80, with higher scores reflecting a more se
Conditions Studied
Interventions
- OTHER Low plant diversity beverage
- OTHER Functional Food intervention
Study Locations (1)
Colorado
- Food and Nutrition Clinical Research Lab - Colorado State University - Fort Collins
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-06-25 |
| Est. Completion | 2026-07 |
| Phase | NA |
What NCT07107269 shows while recruiting
NCT07107269 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 277-participant average among 14 other PTSD - Post Traumatic Stress Disorder trials with a reported enrollment target (86% lower).
The record links to 1 condition, with PTSD - Post Traumatic Stress Disorder appearing as the primary indexed condition, and to 2 interventions - of which Low plant diversity beverage is the first listed.
NCT07107269 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT07107269 about?
NCT07107269 is a clinical study titled "Diet and Microbiome Interactions: Application in Posttraumatic Stress Disorder in Adults Consuming Vegetable Drinks". The gut microbiome has been shown to impact various facets of human health, including mental health. Studies have shown that populations with more agrarian lifestyles tend to have fewer chronic diseases and mental health issues than industrialized populations. A possible factor in these differences ...
What is the current status of trial NCT07107269?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-06-25. Estimated completion is 2026-07.
What conditions does trial NCT07107269 study?
This clinical trial studies the following conditions: PTSD - Post Traumatic Stress Disorder.
What interventions are being tested in trial NCT07107269?
The interventions under investigation include: Low plant diversity beverage (OTHER), Functional Food intervention (OTHER).
Who is sponsoring clinical trial NCT07107269?
This trial is sponsored by Colorado State University, which has 94 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07107269 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for PTSD - Post Traumatic Stress Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07107269's enrollment target sits among peer trials
40 11th of 14 higher than 4 of 14 other PTSD - Post Traumatic Stress Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other PTSD - Post Traumatic Stress Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Treatment for PTSD and Tinnitus
RECRUITING · NA
-
Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD
RECRUITING · NA
-
Transcranial Magnetic Stimulation in Veterans With PTSD
RECRUITING · NA
-
Empowering Perinatal Adolescents Through Writing
RECRUITING · NA
-
Restorative Early Sleep Treatment After the Emergency Department
RECRUITING · NA
-
Evaluating Evidenced Based Options for PTSD Treatment
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01306019 · 40 participants · Phase 1
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
- NCT01608152 · 40 participants
Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors
- NCT01668082 · 40 participants · NA
An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection
- NCT02015013 · 40 participants · Phase 2
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI