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NCT06730841 · ClinicalTrials.gov registry record · NA
Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression
A NA study of Major Depressive Disorder and Treatment-Resistant Depression, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 3
- Enrollment target
- 1
- Study location
NCT06730841: Completed NA study of Major Depressive Disorder and Treatment-Resistant Depression, sponsored by University of California, San Diego.
NCT06730841 is a NA study of Major Depressive Disorder and Treatment-Resistant Depression that has completed, run by University of California, San Diego. The registered enrollment target is 3 participants, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06730841, a NA study of Major Depressive Disorder and Treatment-Resistant Depression, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to evaluate the feasibility, safety, and tolerability of an innovative approach to treating Major Depressive Disorder (MDD), particularly in cases where patients have not responded well to traditional therapies. Specifically, the objective is to evaluate the antidepressant effects of a Dose-Optimized and Spaced Transcranial Direct Current Stimulation (DOS-tDCS) protocol in participants with treatment-resistant depression (TRD) compared to spaced tDCS only and sham tDCS in a 3-arm randomized controlled trial (RCT). The proposed method involves applying low-intensity electrical currents through the scalp in a manner that is both more intense and more frequently spaced than standard treatments. This approach is hypothesized to lead to a significant reduction in depressive symptoms. Participants in the study will be randomly assigned to one of three groups: the experimental group receiving the DOS-tDCS treatment, a group receiving spaced tDCS only, or a control group receiving a sham (placebo) treatment. Outcomes will be measured over a period of six weeks. The study's goal is to offer a potentially more accessible and effective treatment option for individuals who have not benefited from existing MDD therapies.
Primary Outcome
Recruitment rate will be measured as the number of patients enrolled by the conclusion of the study, reported as a whole number.
Conditions Studied
Interventions
- DEVICE Sham Transcranial Direct Current Stimulation
- DEVICE Dose-Optimized and Spaced Transcranial Direct Current Stimulation
- DEVICE Spaced Transcranial Direct Current Stimulation
Study Locations (1)
California
- UCSD Interventional Psychiatry - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2024-09-26 |
| Est. Completion | 2025-09-01 |
| Phase | NA |
What the finished NCT06730841 record still lists
NCT06730841 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 377-participant average among 282 other Major Depressive Disorder trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Major Depressive Disorder appearing as the primary indexed condition, and to 3 interventions - of which Sham Transcranial Direct Current Stimulation is the first listed.
NCT06730841 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06730841 about?
NCT06730841 is a clinical study titled "Dose-Optimized and Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression". This study aims to evaluate the feasibility, safety, and tolerability of an innovative approach to treating Major Depressive Disorder (MDD), particularly in cases where patients have not responded well to traditional therapies. Specifically, the objective is to evaluate the antidepressant effects of...
What is the current status of trial NCT06730841?
This trial is currently completed. It is a NA study. The enrollment target is 3 participants. The study started on 2024-09-26. Estimated completion is 2025-09-01.
What conditions does trial NCT06730841 study?
This clinical trial studies the following conditions: Major Depressive Disorder, Treatment-Resistant Depression.
What interventions are being tested in trial NCT06730841?
The interventions under investigation include: Sham Transcranial Direct Current Stimulation (DEVICE), Dose-Optimized and Spaced Transcranial Direct Current Stimulation (DEVICE), Spaced Transcranial Direct Current Stimulation (DEVICE).
Who is sponsoring clinical trial NCT06730841?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06730841 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Major Depressive Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06730841's enrollment target sits among peer trials
3 282nd of 282 the lowest of 282 other Major Depressive Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Major Depressive Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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