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NCT06730750 · ClinicalTrials.gov registry record · Phase 1

A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors

A Phase 1 study of Advanced Solid Tumors, sponsored by Bristol-Myers Squibb.

Recruiting
Registry status
Phase 1
Development phase
360
Enrollment target
6
Study locations

NCT06730750 is a Phase 1 study of Advanced Solid Tumors that is actively recruiting participants, run by Bristol-Myers Squibb. The registered enrollment target is 360 participants, above the 196-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (84% higher). The trial reports 6 study locations across 6 states.

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The verdict

NCT06730750, a Phase 1 study of Advanced Solid Tumors, is actively recruiting participants, sponsored by Bristol-Myers Squibb.

RECRUITING
Registry status
Phase 1
Development phase
360 participants
Enrollment target
6
Study locations

Study Summary

This is a study of BMS-986490 as a monotherapy and in combination with bevacizumab in participants with select advanced solid tumors known to express CEACAM5.

Conditions Studied

Advanced Solid Tumors

Interventions

  • DRUG Bevacizumab
  • DRUG BMS-986490

Study Locations (6)

California

  • USC/Norris Comprehensive Cancer Center - Los Angeles

Michigan

  • START Midwest - Grand Rapids

New Jersey

  • John Theurer Cancer Center at Hackensack University Medical Center - Hackensack

Pennsylvania

  • UPMC Hillman Cancer Center - Pittsburgh

Queensland

  • Tasman Oncology Research - Southport

Ontario

  • Princess Margaret Cancer Centre - Toronto

Trial Details

FieldValue
Enrollment Target 360 participants
Start Date 2025-02-12
Est. Completion 2029-12-09
Phase Phase 1

Sponsor

Bristol-Myers Squibb

1,025 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06730750

The ClinicalTrials.gov registry entry for NCT06730750 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 360 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 196-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (84% higher). The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 2 interventions - of which Bevacizumab is the first listed.

NCT06730750 reports 6 study locations spanning 6 distinct geographic areas - top geographies include California, Michigan, New Jersey.

Frequently Asked Questions

What is clinical trial NCT06730750 about?

NCT06730750 is a clinical study titled "A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors". This is a study of BMS-986490 as a monotherapy and in combination with bevacizumab in participants with select advanced solid tumors known to express CEACAM5.

What is the current status of trial NCT06730750?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 360 participants. The study started on 2025-02-12. Estimated completion is 2029-12-09.

What conditions does trial NCT06730750 study?

This clinical trial studies the following conditions: Advanced Solid Tumors.

What interventions are being tested in trial NCT06730750?

The interventions under investigation include: Bevacizumab (DRUG), BMS-986490 (DRUG).

Who is sponsoring clinical trial NCT06730750?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06730750 being conducted?

This trial has 6 study locations across California, Michigan, New Jersey, Pennsylvania, Queensland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.