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NCT06693986 · ClinicalTrials.gov registry record · Phase 1

Adenovirus (RGDCRAdCOX2F)

A Phase 1 study of Adenocarcinoma of Pancreas, sponsored by Masonic Cancer Center, University of Minnesota.

Recruiting
Registry status
Phase 1
Development phase
18
Enrollment target
1
Study location

NCT06693986: Recruiting Phase 1 study of Adenocarcinoma of Pancreas, sponsored by Masonic Cancer Center, University of Minnesota.

NCT06693986 is a Phase 1 study of Adenocarcinoma of Pancreas that is actively recruiting participants, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06693986, a Phase 1 study of Adenocarcinoma of Pancreas, is actively recruiting participants, sponsored by Masonic Cancer Center, University of Minnesota.

RECRUITING
Registry status
Phase 1
Development phase
18 participants
Enrollment target
1
Study location

Study Summary

This is a single center, Phase I dose finding study of a single direct tumor injection of an RGD modified conditionally replicative adenovirus (RGDCRAdcox2F) in persons with adenocarcinoma of the pancreas. The study is designed to determine the MTD of RGDCRAdCOX2F that corresponds to the maximum desired toxicity of ≤ 20%.

Conditions Studied

Interventions

  • BIOLOGICAL Replicative Adenovirus Vector (RGDCRAdCOX2F)

Study Locations (1)

Minnesota

  • Masonic Cancer Center - Minneapolis

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2024-12-27
Est. Completion 2029-10-15
Phase Phase 1

What NCT06693986 shows while recruiting

NCT06693986 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).

The record links to 1 condition, with Adenocarcinoma of Pancreas appearing as the primary indexed condition, and to 1 intervention - of which Replicative Adenovirus Vector (RGDCRAdCOX2F) is the first listed.

NCT06693986 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT06693986 about?

NCT06693986 is a clinical study titled "Adenovirus (RGDCRAdCOX2F)". This is a single center, Phase I dose finding study of a single direct tumor injection of an RGD modified conditionally replicative adenovirus (RGDCRAdcox2F) in persons with adenocarcinoma of the pancreas. The study is designed to determine the MTD of RGDCRAdCOX2F that corresponds to the maximum des...

What is the current status of trial NCT06693986?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2024-12-27. Estimated completion is 2029-10-15.

What conditions does trial NCT06693986 study?

This clinical trial studies the following conditions: Adenocarcinoma of Pancreas.

What interventions are being tested in trial NCT06693986?

The interventions under investigation include: Replicative Adenovirus Vector (RGDCRAdCOX2F) (BIOLOGICAL).

Who is sponsoring clinical trial NCT06693986?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06693986 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT06693986's enrollment target sits among peer trials

18 1721st of 2000 higher than 216 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06693986, the US trial registry maintained by the National Library of Medicine. NCT06693986 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.