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RECRUITING Phase 2

Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease

NCT06989359 · View on ClinicalTrials.gov ↗

Study Summary

This Phase 2 study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated kidney diseases.

Interventions

  • DRUG ADX-038 Dose Level 2
  • DRUG ADX-038 Dose Level 1

Study Locations (12)

Other

  • ADARx Clinical Site — Pok Fu Lam
  • ADARx Clinical Site — Shatin
  • ADARx Clinical Site — Cheonan
  • ADARx Clinical Site — Seoul

New South Wales

  • ADARx Clinical Site — Wollongong
  • ADARx Clinical Site — Gyeonggi-do
  • ADARx Clinical Site — Seoul

Texas

  • ADARx Clinical Site — Dallas
  • ADARx Clinical Site — Houston

Louisiana

  • ADARx Clinical Site — Shreveport

Michigan

  • ADARx Clinical Site — Shelby

South Dakota

  • ADARx Clinical Site — Dakota Dunes

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2025-08-28
Est. Completion 2028-07
Phase Phase 2

Sponsor

ADARx Pharmaceuticals

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06989359

The ClinicalTrials.gov registry entry for NCT06989359 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ADARx Pharmaceuticals, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 5 conditions, with IgAN appearing as the primary indexed condition, and to 2 interventions — of which ADX-038 Dose Level 2 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06989359 reports 12 study locations spanning 6 distinct geographic areas — top geographies include Other, New South Wales, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06989359 about?

NCT06989359 is a clinical study titled "Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease". This Phase 2 study is designed to assess the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of ADX-038 in adults with complement-mediated kidney diseases.

What is the current status of trial NCT06989359?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 45 participants. The study started on 2025-08-28. Estimated completion is 2028-07.

What conditions does trial NCT06989359 study?

This clinical trial studies the following conditions: IgAN, C3G, IC-MPGN, IgA Nephropathy (IgAN), Complement-mediated Kidney Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06989359?

The interventions under investigation include: ADX-038 Dose Level 2 (DRUG), ADX-038 Dose Level 1 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06989359?

This trial is sponsored by ADARx Pharmaceuticals, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06989359 being conducted?

This trial has 12 study locations across Louisiana, Michigan, South Dakota, Texas, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial