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NCT06672718 · ClinicalTrials.gov registry record · Phase 1

A Study of SPY002-091 in Healthy Volunteers

A Phase 1 study of Healthy, sponsored by Spyre Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
56
Enrollment target
1
Study location

NCT06672718 is a Phase 1 study of Healthy that is actively recruiting participants, run by Spyre Therapeutics. The registered enrollment target is 56 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06672718, a Phase 1 study of Healthy, is actively recruiting participants, sponsored by Spyre Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
56 participants
Enrollment target
1
Study location

Study Summary

This is a Phase 1, randomized, double-blind, placebo-controlled, single- dose, first in human safety, tolerability, and pharmacokinetic study of SPY002-091 in healthy participants.

Conditions Studied

Interventions

  • OTHER Placebo
  • DRUG SPY002-091

Study Locations (1)

California

  • Spyre Site 1 - Cypress

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2024-11-26
Est. Completion 2026-06-22
Phase Phase 1

Sponsor

Spyre Therapeutics

6 total trials

What the Registry Record Tells You About NCT06672718

The ClinicalTrials.gov registry entry for NCT06672718 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (91% lower). The listed sponsor is Spyre Therapeutics, which has 6 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT06672718 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06672718 about?

NCT06672718 is a clinical study titled "A Study of SPY002-091 in Healthy Volunteers". This is a Phase 1, randomized, double-blind, placebo-controlled, single- dose, first in human safety, tolerability, and pharmacokinetic study of SPY002-091 in healthy participants.

What is the current status of trial NCT06672718?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 56 participants. The study started on 2024-11-26. Estimated completion is 2026-06-22.

What conditions does trial NCT06672718 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT06672718?

The interventions under investigation include: Placebo (OTHER), SPY002-091 (DRUG).

Who is sponsoring clinical trial NCT06672718?

This trial is sponsored by Spyre Therapeutics, which has 6 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06672718 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.