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NCT06659991 · ClinicalTrials.gov registry record · Early Phase 1
JIT: Effect of Pain on DT in TMD
A Early Phase 1 study of Temporomandibular Disorder (TMD), sponsored by University of Minnesota.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 160
- Enrollment target
- 1
- Study location
NCT06659991: Recruiting Early Phase 1 study of Temporomandibular Disorder (TMD), sponsored by University of Minnesota.
NCT06659991 is a Early Phase 1 study of Temporomandibular Disorder (TMD) that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 160 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (202% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06659991, a Early Phase 1 study of Temporomandibular Disorder (TMD), is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 160 participants
- Enrollment target
- 1
- Study location
Study Summary
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and non-modifiable risk factors, including orofacial pain status, have been conducted. This project addresses this gap in knowledge by determining the effect of pain on drinking topography in heavy drinkers with and without chronic TMD pain in both the laboratory and daily life.
Primary Outcome
Variables reflecting microstructure of alcohol use during self-administration, including sip interval and sip volume.
Conditions Studied
Interventions
- DRUG alcohol condition
- OTHER control condition
Study Locations (1)
Minnesota
- University of Minnesota - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2025-05-14 |
| Est. Completion | 2029-09-07 |
| Phase | Early Phase 1 |
What NCT06659991 shows while recruiting
NCT06659991 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (202% higher).
The record links to 1 condition, with Temporomandibular Disorder (TMD) appearing as the primary indexed condition, and to 2 interventions - of which alcohol condition is the first listed.
NCT06659991 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06659991 about?
NCT06659991 is a clinical study titled "JIT: Effect of Pain on DT in TMD". Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in many individuals. However, few systematic examinations of modifiable and n...
What is the current status of trial NCT06659991?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 160 participants. The study started on 2025-05-14. Estimated completion is 2029-09-07.
What conditions does trial NCT06659991 study?
This clinical trial studies the following conditions: Temporomandibular Disorder (TMD).
What interventions are being tested in trial NCT06659991?
The interventions under investigation include: alcohol condition (DRUG), control condition (OTHER).
Who is sponsoring clinical trial NCT06659991?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06659991 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06659991's enrollment target sits among peer trials
160 88th of 2000 higher than 1,907 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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