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NCT04936308 · ClinicalTrials.gov registry record · Phase 3
Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent
A Phase 3 study of Arthritis, Psoriatic, sponsored by Janssen Research & Development.
- Active
- Registry status
- Phase 3
- Development phase
- 453
- Enrollment target
- 20
- Study locations
NCT04936308 is a Phase 3 study of Arthritis, Psoriatic that is active but no longer recruiting, run by Janssen Research & Development. The registered enrollment target is 453 participants, below the 548-participant average among 16 other Arthritis, Psoriatic trials with a reported enrollment target (17% lower). The trial reports 20 study locations across 7 states.
The verdict
NCT04936308, a Phase 3 study of Arthritis, Psoriatic, is active but no longer recruiting, sponsored by Janssen Research & Development.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 453 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Guselkumab
Study Locations (20)
Florida
- Bay Pines VA Healthcare System - Bay Pines
- Clinical Research of West Florida - Clearwater
- Omega Research Consultants - DeBary
- Advanced Clinical Research of Orlando - Ocoee
- Integral Rheumatology And Immunology Specialists - Plantation
- Clinical Research of West Florida 1 - Tampa
- Florida Medical Clinic, P.A. - Zephyrhills
Arizona
- Arizona Arthritis and Rheumatology Research PLLC 2 - Avondale
- Arizona Arthritis and Rheumatology Research PLLC 3 - Flagstaff
- Arizona Arthritis and Rheumatology Research PLLC - Mesa
- Arizona Arthritis and Rheumatology Research PLLC 1 - Phoenix
- Arizona Arthritis and Rheumatology Associates - Sun City
- Southern Arizona VA Healthcare System - Tucson
California
- Newport Huntington Medical Group - Huntington Beach
- Medvin Clinical Research 2 - Thousand Oaks
- Medvin Clinical Research - Tujunga
Alabama
- Arthritis Associates - Mountain Brook
Arkansas
- Unity Health-White County Medical Center - Searcy
Connecticut
- Clinical Research Center of Connecticut - Danbury
Illinois
- Great Lakes Clinical Trials - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 453 participants |
| Start Date | 2021-09-28 |
| Est. Completion | 2026-07-16 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04936308
The ClinicalTrials.gov registry entry for NCT04936308 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 453 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 548-participant average among 16 other Arthritis, Psoriatic trials with a reported enrollment target (17% lower). The listed sponsor is Janssen Research & Development, which has 593 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Arthritis, Psoriatic appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04936308 reports 20 study locations spanning 7 distinct geographic areas - top geographies include Florida, Arizona, California.
Frequently Asked Questions
What is clinical trial NCT04936308 about?
NCT04936308 is a clinical study titled "Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent". The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.
What is the current status of trial NCT04936308?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 453 participants. The study started on 2021-09-28. Estimated completion is 2026-07-16.
What conditions does trial NCT04936308 study?
This clinical trial studies the following conditions: Arthritis, Psoriatic.
What interventions are being tested in trial NCT04936308?
The interventions under investigation include: Placebo (DRUG), Guselkumab (DRUG).
Who is sponsoring clinical trial NCT04936308?
This trial is sponsored by Janssen Research & Development, which has 593 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04936308 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.