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NCT06637436 · ClinicalTrials.gov registry record · NA
PrEP Readiness Interventions for Sustained Motivation (PRISM)
A NA study of HIV and Methamphetamine Disorders, sponsored by Florida International University.
- Recruiting
- Registry status
- NA
- Development phase
- 400
- Enrollment target
- 2
- Study locations
NCT06637436: Recruiting NA study of HIV and Methamphetamine Disorders, sponsored by Florida International University.
NCT06637436 is a NA study of HIV and Methamphetamine Disorders that is actively recruiting participants, run by Florida International University. The registered enrollment target is 400 participants, roughly in line with the 439-participant average among 303 other HIV trials with a reported enrollment target. The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06637436, a NA study of HIV and Methamphetamine Disorders, is actively recruiting participants, sponsored by Florida International University.
- RECRUITING
- Registry status
- NA
- Development phase
- 400 participants
- Enrollment target
- 2
- Study locations
Study Summary
This is a hybrid type I, factorial randomized controlled trial to test the comparative and combined effectiveness of contingency management (CM) alone or CM with motivational interviewing (MI) for optimizing entry or re-entry into the PrEP care continuum. A total of 400 participants will be randomized to CM (n = 200) or MI+CM (n = 200), all delivered via Telehealth. Monthly follow-up assessments will be completed over 12 months to examine differential effectiveness for the primary outcome - filling a PrEP prescription (verified using a digital photo or detectable tenofovir diphosphate). Secondary outcomes will include: self-reported PrEP clinical evaluation by a PrEP provider; self-reported meth and other substance use severity (ASSIST), and self-reported receptive and insertive condomless anal sex (CAS).
Primary Outcome
The proportion of participants providing evidence of PrEP or ART use (i.e., a digital photo a medication bottle bearing their name OR evidence of receipt of medication from a medical record)
Conditions Studied
Interventions
- BEHAVIORAL Contingency Management (CM)
- BEHAVIORAL Motivational Interviewing (MI)
Study Locations (2)
Florida
- Florida International University Stempel College of Public Health and Social Work - Miami
- Florida International University - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2025-01-28 |
| Est. Completion | 2028-04-30 |
| Phase | NA |
What NCT06637436 shows while recruiting
NCT06637436 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 439-participant average among 303 other HIV trials with a reported enrollment target.
The record links to 2 conditions, with HIV appearing as the primary indexed condition, and to 2 interventions - of which Contingency Management (CM) is the first listed.
NCT06637436 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06637436 about?
NCT06637436 is a clinical study titled "PrEP Readiness Interventions for Sustained Motivation (PRISM)". This is a hybrid type I, factorial randomized controlled trial to test the comparative and combined effectiveness of contingency management (CM) alone or CM with motivational interviewing (MI) for optimizing entry or re-entry into the PrEP care continuum. A total of 400 participants will be randomiz...
What is the current status of trial NCT06637436?
This trial is currently recruiting. It is a NA study. The enrollment target is 400 participants. The study started on 2025-01-28. Estimated completion is 2028-04-30.
What conditions does trial NCT06637436 study?
This clinical trial studies the following conditions: HIV, Methamphetamine Disorders.
What interventions are being tested in trial NCT06637436?
The interventions under investigation include: Contingency Management (CM) (BEHAVIORAL), Motivational Interviewing (MI) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06637436?
This trial is sponsored by Florida International University, which has 89 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06637436 being conducted?
This trial has 2 study locations across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06637436's enrollment target sits among peer trials
400 39th of 303 higher than 257 of 303 other HIV trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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