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NCT06627894 · ClinicalTrials.gov registry record · NA
Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU)
A NA study of Depression and Cognitive Decline, sponsored by Indiana University.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 2
- Study locations
NCT06627894 is a NA study of Depression and Cognitive Decline that is actively recruiting participants, run by Indiana University. The registered enrollment target is 300 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT06627894, a NA study of Depression and Cognitive Decline, is actively recruiting participants, sponsored by Indiana University.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 2
- Study locations
Study Summary
Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer's disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with Internet CBT to Slow Cognitive Decline in Older ICU Survivors), which will test the efficacy of an internet CBT intervention called Good Days Ahead (GDA) to reduce the burden of subjective cognitive decline (SCD) in older ICU survivors with moderate to severe depressive symptoms after ICU hospitalization.
Conditions Studied
Interventions
- BEHAVIORAL Active Control
- BEHAVIORAL Therapist-Assisted Internet Cognitive-Behavioral Therapy for Depression
Study Locations (2)
Indiana
- Eskenazi Hospital - Indianapolis
- IU Health Methodist Hospital - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2025-03-13 |
| Est. Completion | 2029-10-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06627894
The ClinicalTrials.gov registry entry for NCT06627894 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (62% lower). The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Active Control is the first listed.
NCT06627894 reports 2 study locations spanning 1 distinct geographic area - top geographies include Indiana.
Frequently Asked Questions
What is clinical trial NCT06627894 about?
NCT06627894 is a clinical study titled "Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU)". Depression affects one-third of intensive care unit (ICU) survivors and represents a potentially modifiable target to slow cognitive decline and reduce the risk of Alzheimer's disease and related dementias (ADRD). Our multi-PI team proposes a two-arm RCT called ADEPT-ICU (Attenuating DEPression with...
What is the current status of trial NCT06627894?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2025-03-13. Estimated completion is 2029-10-30.
What conditions does trial NCT06627894 study?
This clinical trial studies the following conditions: Depression, Cognitive Decline.
What interventions are being tested in trial NCT06627894?
The interventions under investigation include: Active Control (BEHAVIORAL), Therapist-Assisted Internet Cognitive-Behavioral Therapy for Depression (BEHAVIORAL).
Who is sponsoring clinical trial NCT06627894?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06627894 being conducted?
This trial has 2 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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