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NCT06623409 · ClinicalTrials.gov registry record · Phase 1
Safety and Immunogenicity of V540B in Healthy Adults (V540B-002).
A Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
- Active
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
- 5
- Study locations
NCT06623409: Active Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
NCT06623409 is a Phase 1 study of Healthy that is active but no longer recruiting, run by Merck Sharp & Dohme. The registered enrollment target is 72 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (89% lower). The trial reports 5 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06623409, a Phase 1 study of Healthy, is active but no longer recruiting, sponsored by Merck Sharp & Dohme.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
- 5
- Study locations
Study Summary
Researchers are looking for new ways to prevent cancers related to human papillomavirus (HPV). HPV is a common virus that can cause an infection. There are many different types of HPV. Most people's immune system can fight HPV infection and it goes away without treatment. For some people, HPV infections can last longer and may cause cancer years later. A standard vaccine to prevent HPV-related cancers is GARDASIL®9 (G9). G9 protects against 9 types of HPV but it does not protect against other types of HPV. The study vaccine (called V540B) is designed to protect against the same HPV types that G9 protects against plus other HPV types. The main goal of this study is to learn about the safety of V540B in healthy adults and if people tolerate it.
Primary Outcome
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.
Conditions Studied
Interventions
- BIOLOGICAL GARDASIL®9 (G9)
- BIOLOGICAL V540B
Study Locations (5)
California
- Anaheim Clinical Trials ( Site 0002) - Anaheim
- California Clinical Trials Medical Group managed by PAREXEL ( Site 0008) - Glendale
Florida
- Velocity Clinical Research, Hallandale Beach ( Site 0003) - Hallandale
- Research Centers of America ( Hollywood ) ( Site 0001) - Hollywood
Nebraska
- Velocity Clinical Research, Omaha ( Site 0005) - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2024-11-12 |
| Est. Completion | 2026-11-20 |
| Phase | Phase 1 |
What the registry record for NCT06623409 still lists
NCT06623409 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (89% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which GARDASIL®9 (G9) is the first listed.
NCT06623409 lists 5 locations in 3 states (California, Florida, Nebraska).
Frequently Asked Questions
What is clinical trial NCT06623409 about?
NCT06623409 is a clinical study titled "Safety and Immunogenicity of V540B in Healthy Adults (V540B-002).". Researchers are looking for new ways to prevent cancers related to human papillomavirus (HPV). HPV is a common virus that can cause an infection. There are many different types of HPV. Most people's immune system can fight HPV infection and it goes away without treatment. For some people, HPV infect...
What is the current status of trial NCT06623409?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2024-11-12. Estimated completion is 2026-11-20.
What conditions does trial NCT06623409 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT06623409?
The interventions under investigation include: GARDASIL®9 (G9) (BIOLOGICAL), V540B (BIOLOGICAL).
Who is sponsoring clinical trial NCT06623409?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06623409 being conducted?
This trial has 5 study locations across California, Florida, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06623409's enrollment target sits among peer trials
72 314th of 1090 higher than 770 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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