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NCT06621329 · ClinicalTrials.gov registry record · Phase 2

Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache

A Phase 2 study of Headache and SAH (Subarachnoid Hemorrhage), sponsored by University of California, Davis.

Recruiting
Registry status
Phase 2
Development phase
40
Enrollment target
1
Study location

NCT06621329: Recruiting Phase 2 study of Headache and SAH (Subarachnoid Hemorrhage), sponsored by University of California, Davis.

NCT06621329 is a Phase 2 study of Headache and SAH (Subarachnoid Hemorrhage) that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 40 participants, below the 154-participant average among 35 other Headache trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06621329, a Phase 2 study of Headache and SAH (Subarachnoid Hemorrhage), is actively recruiting participants, sponsored by University of California, Davis.

RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The study titled \"Transnasal sphenopalatine ganglion block for treatment of acute subarachnoid hemorrhage associated headache\" is a randomized controlled pilot study aimed at evaluating the efficacy of a transnasal sphenopalatine ganglion (SPG) block in addition to standard pain medication for reducing headache severity in patients with acute subarachnoid hemorrhage (aSAH). The study also examines whether this intervention can reduce opioid requirements during hospitalization and upon discharge.

Primary Outcome

Pain scores will be obtained at regular intervals to compare pain control between the two arms. Pain scores will be collected multiple times throughout each ICU day, up to ICU day 14.

Interventions

  • COMBINATION_PRODUCT Transnasal sphenopalatine ganglion block

Study Locations (1)

California

  • UC Davis Medical Center - Sacramento

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2024-10-17
Est. Completion 2026-10
Phase Phase 2
University of California, Davis

657 total trials

What NCT06621329 shows while recruiting

NCT06621329 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 154-participant average among 35 other Headache trials with a reported enrollment target (74% lower).

The record links to 2 conditions, with Headache appearing as the primary indexed condition, and to 1 intervention - of which Transnasal sphenopalatine ganglion block is the first listed.

NCT06621329 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06621329 about?

NCT06621329 is a clinical study titled "Transnasal Sphenopalatine Ganglion Block for Treatment of Acute Subarachnoid Hemorrhage Associated Headache". The study titled \"Transnasal sphenopalatine ganglion block for treatment of acute subarachnoid hemorrhage associated headache\" is a randomized controlled pilot study aimed at evaluating the efficacy of a transnasal sphenopalatine ganglion (SPG) block in addition to standard pain medication...

What is the current status of trial NCT06621329?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2024-10-17. Estimated completion is 2026-10.

What conditions does trial NCT06621329 study?

This clinical trial studies the following conditions: Headache, SAH (Subarachnoid Hemorrhage).

What interventions are being tested in trial NCT06621329?

The interventions under investigation include: Transnasal sphenopalatine ganglion block (COMBINATION_PRODUCT).

Who is sponsoring clinical trial NCT06621329?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06621329 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Headache

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06621329's enrollment target sits among peer trials

40 24th of 35 higher than 11 of 35 other Headache trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Headache trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06621329, the US trial registry maintained by the National Library of Medicine. NCT06621329 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.