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NCT06008795 · ClinicalTrials.gov registry record · Phase 2
BLOCK-SAH - PPF-Block for Post-SAH Headache
A Phase 2 study of Headache and Subarachnoid Hemorrhage, Aneurysmal, sponsored by University of Florida.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 195
- Enrollment target
- 11
- Study locations
NCT06008795: Recruiting Phase 2 study of Headache and Subarachnoid Hemorrhage, Aneurysmal, sponsored by University of Florida.
NCT06008795 is a Phase 2 study of Headache and Subarachnoid Hemorrhage, Aneurysmal that is actively recruiting participants, run by University of Florida. The registered enrollment target is 195 participants, above the 150-participant average among 35 other Headache trials with a reported enrollment target (30% higher). The trial reports 11 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06008795, a Phase 2 study of Headache and Subarachnoid Hemorrhage, Aneurysmal, is actively recruiting participants, sponsored by University of Florida.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 195 participants
- Enrollment target
- 11
- Study locations
Study Summary
BLOCK-SAH is a phase II, multicenter, randomized, double-blinded, placebo-controlled clinical trial with a sequential parallel comparison design (SPCD) of bilateral pterygopalatine fossa (PPF) injections with 20mg ropivacaine + 4mg dexamethasone (active, PPF-block) compared to saline (placebo) for headache in survivors of aneurysmal subarachnoid hemorrhage (SAH), while monitoring intracranial arterial mean flow velocities with transcranial Doppler (TCD) peri-intervention (intervention = PPF-injections: active or placebo)
Primary Outcome
prn oral morphine equivalent (OME)/day use
Conditions Studied
Interventions
- DRUG Pterygopalatine Fossa Nerve Block with Ropivacaine and Dexamethasone
- PROCEDURE Placebo Pteryogpalatine Fossa Injection
Study Locations (11)
New York
- Albany Medical College - Albany
- University of Rochester Medical College - Rochester
Florida
- University of Florida - Gainesville
Georgia
- Emory University - Atlanta
Maryland
- University of Maryland Baltimore - Baltimore
Minnesota
- Mayo Clinic - Rochester
Ohio
- University of Cincinnati - Cincinnati
Oregon
- Oregon Health and Sciences University - Portland
Pennsylvania
- Thomas Jefferson University - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 195 participants |
| Start Date | 2023-12-17 |
| Est. Completion | 2027-02-28 |
| Phase | Phase 2 |
What NCT06008795 shows while recruiting
NCT06008795 is an interventional study that assigns participants to a tested intervention. The registered 195 participants enrollment target is mid-sized for trials with a published cap, above the 150-participant average among 35 other Headache trials with a reported enrollment target (30% higher).
The record links to 2 conditions, with Headache appearing as the primary indexed condition, and to 2 interventions - of which Pterygopalatine Fossa Nerve Block with Ropivacaine and Dexamethasone is the first listed.
NCT06008795 lists 11 locations in 10 states (New York, Florida, Georgia).
Frequently Asked Questions
What is clinical trial NCT06008795 about?
NCT06008795 is a clinical study titled "BLOCK-SAH - PPF-Block for Post-SAH Headache". BLOCK-SAH is a phase II, multicenter, randomized, double-blinded, placebo-controlled clinical trial with a sequential parallel comparison design (SPCD) of bilateral pterygopalatine fossa (PPF) injections with 20mg ropivacaine + 4mg dexamethasone (active, PPF-block) compared to saline (placebo) for h...
What is the current status of trial NCT06008795?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 195 participants. The study started on 2023-12-17. Estimated completion is 2027-02-28.
What conditions does trial NCT06008795 study?
This clinical trial studies the following conditions: Headache, Subarachnoid Hemorrhage, Aneurysmal.
What interventions are being tested in trial NCT06008795?
The interventions under investigation include: Pterygopalatine Fossa Nerve Block with Ropivacaine and Dexamethasone (DRUG), Placebo Pteryogpalatine Fossa Injection (PROCEDURE).
Who is sponsoring clinical trial NCT06008795?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06008795 being conducted?
This trial has 11 study locations across Florida, Georgia, Maryland, Minnesota, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Headache
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06008795's enrollment target sits among peer trials
195 7th of 35 higher than 29 of 35 other Headache trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Headache trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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